Results 61 to 70 of about 885,674 (267)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Hierarchical Target Tracking for Unmanned Aerial Vehicle Swarms with Distributed Optimization and Affine Control

Drones
Target tracking of unmanned aerial vehicle (UAV) swarms remains a significant challenge due to highly maneuverable target swarms and complex environments.
Han Wang, Xiaolong Liang, Jiaqiang Zhang, Yueqi Hou, Aiwu Yang   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Research on Integrated Decision-Control Cooperative Target Assignment for Cross-Domain Unmanned Systems Based on a Bi-Level Optimization Framework

Drones
Addressing prevalent challenges in current cooperative task assignment methods for cross-domain unmanned swarm, such as the disconnection between decision-making and execution processes, and the inadequate incorporation of platform kinematic constraints,
Aoyu Zheng, Xiaolong Liang, Zhiyang Zhang, Yuyan Xiao, Jiaqiang Zhang   +4 more
doaj   +1 more source

Evaluation Method of Usability of Low Altitude Airspace ResourcesBased on the Regression Analysis

Hangkong gongcheng jinzhan, 2019
Low altitude airspace resources has always been the development bottleneck of the general aviation industry, and is also one of the key factors in restricting the development of general aviation in China. Based on theoretical research and field research,
Wang Zekun, Wu Minggong, Wen Xiangxi, Nie Dangmin, Jiang Xurui   +4 more
doaj   +1 more source

Force control in chronic stroke

Neuroscience & Biobehavioral Reviews, 2015
Force control deficits are common dysfunctions after a stroke. This review concentrates on various force control variables associated with motor impairments and suggests new approaches to quantifying force control production and modulation. Moreover, related neurophysiological mechanisms were addressed to determine variables that affect force control ...
Nyeonju, Kang, Kang, Nyeonju, Cauraugh, James H.   +2 more
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Deception mechanisms of FDA‒AWACS against passive monopulse angle measurements

IET Radar, Sonar & Navigation
Airborne warning and control systems (AWACS) serve as critical command and control centres in air combat operations, making them prime targets for strategic attacks.
Bo Wang, Gang Wang, Yonglin Li, Rennong Yang, Yu Zhao   +4 more
doaj   +1 more source

A Spatio-Temporally Cooperative Guidance Law for Highly Maneuverable Target

Aerospace
Conventional guidance laws often exhibit difficulty in approaching highly maneuverable targets and suffer from poor robustness. To address these limitations, this paper proposes a spatio-temporally consistent cooperative guidance method based on the ...
Jia Liu, Yang Guo, Shaobo Wang, Shiyuan Zhang, Jimao Sang, Chengyi Zhang   +5 more
doaj   +1 more source