Results 51 to 60 of about 885,674 (267)

Constrained Optimization and Dynamic Trade-Off Method for Formation Assignment of Heterogeneous UAV Swarms

Drones
This paper addresses the formation assignment problem for heterogeneous UAV swarms in dynamic mission environments. A constrained optimization model is constructed in which UAV capabilities are divided into shareable and exclusive types; a neighborhood ...
Zhenxing Zhang, Liping Hu, Dongwei Zhang, Rennong Yang, Ying Wang, Jialiang Zuo   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Optimal Sensor Deployment and Velocity Configuration With Hybrid TDOA and FDOA Measurements

IEEE Access, 2019
Source localization based on the hybrid time-difference-of-arrival (TDOA) and frequency-difference-of-arrival (FDOA) measurements from distributed sensors is an essential problem in wireless sensor networks (WSNs).
Weijia Wang, Peng Bai, Yubing Wang, Xiaolong Liang, Jiaqiang Zhang   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Priority-Aware Multi-Runway UAV Sequencing for Disaster Relief Operations: Reinforcement Learning with Emergent Runway Specialisation Under Operational Constraints

Aerospace
Multi-runway sequencing of unmanned aerial vehicles (UAVs) at temporary disaster relief aerodromes presents a priority-heterogeneous scheduling problem under class-asymmetric wake turbulence constraints.
Jia Peng, Yarong Wu, Chenjie Wei, Yang Ou, Hao Wang, Miaomiao Zhu   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Road Extraction by Using Atrous Spatial Pyramid Pooling Integrated Encoder-Decoder Network and Structural Similarity Loss

Remote Sensing, 2019
The technology used for road extraction from remote sensing images plays an important role in urban planning, traffic management, navigation, and other geographic applications.
Hao He, Dongfang Yang, Shicheng Wang, Shuyang Wang, Yongfei Li   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Identification Method of Critical Routes in Aviation Network Based on Double Capacity Identification Standard

Hangkong gongcheng jinzhan, 2019
A method of identifying critical routes in the aviation network based on dual capacity identification standard is used for improving the singleness of the traditional identification method and incomplete evaluation index of network performance.
Li Jiawei, Liu Fei, Wu Minggong, Yu Minjian, Kang Runzhe   +4 more
doaj   +1 more source