Results 71 to 80 of about 844,204 (267)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Accurate semi‐direct lidar‐inertial odometry based on distance and normal direction

Electronics Letters
To improve the autonomous navigation capability of unmanned platforms, an accurate semi‐direct lidar‐inertial odometry algorithm with a new point cloud alignment evaluation metric is proposed.
Erliang Yao, Haitao Song, Jing Zhao
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Unified force-impedance control

The International Journal of Robotics Research
Unified force-impedance control (UFIC) aims at integrating the advantages of impedance control and force control. Compliance and exact force regulation are equally important abilities in modern robot manipulation. The developed passivity-based framework builds on the energy tank concept and is suitable for serial rigid and flexible-joint robots ...
Sami Haddadin, Erfan Shahriari
openaire   +1 more source

Research on methods to enhance the survivability of AWACS with FDA against anti‐ARMs on a battlefield

IET Microwaves, Antennas & Propagation
The Airborne Warning and Control System (AWACS) are pivotal assets in aerial operations, necessitating specialised protection measures, and serving as prime targets for enemy anti‐radiation missiles (ARMs).
Bo Wang, Gang Wang, Rengnong Yang, Yonglin Li, Yu Zhao   +4 more
doaj   +1 more source

A Multi-Fidelity Data Fusion Approach Based on Semi-Supervised Learning for Image Super-Resolution in Data-Scarce Scenarios

Sensors
Image super-resolution (SR) techniques can significantly enhance visual quality and information density. However, existing methods often rely on large amounts of paired low- and high-resolution (LR-HR) data, which limits their generalization and ...
Hongzheng Zhu, Yingjuan Zhao, Ximing Qiao, Jinshuo Zhang, Jingnan Ma, Sheng Tong   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Force control in chronic stroke

Neuroscience & Biobehavioral Reviews, 2015
Force control deficits are common dysfunctions after a stroke. This review concentrates on various force control variables associated with motor impairments and suggests new approaches to quantifying force control production and modulation. Moreover, related neurophysiological mechanisms were addressed to determine variables that affect force control ...
Nyeonju, Kang, Kang, Nyeonju, Cauraugh, James H.   +2 more
openaire   +3 more sources

An Unsupervised Situation Awareness Framework for UAV Sensor Data Fusion Enabled by a Stabilized Deep Variational Autoencoder

Sensors
Effective situation awareness relies on the robust processing of high-dimensional data streams generated by onboard sensors. However, the application of deep generative models to extract features from complex UAV sensor data (e.g., GPS, IMU, and radar ...
Anxin Guo, Zhenxing Zhang, Rennong Yang, Ying Zhang, Liping Hu, Leyan Li   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source