Results 41 to 50 of about 222,458 (258)
Development and Validation of a System for Game Control Based on a Force Plate
Applied Sciences, 2023 A force plate is a device that measures the ground reaction force caused by a shift in the human body’s center of mass (CoM). Using a controlled change in the human body’s CoM, the human body’s center of pressure (CoP) is shifted in a 2D plane, along ...
Zoran Vrhovski +3 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Research on Cutting Characteristics of Rock Plate with Two Sides Fixed and Two Sides Free
Advances in Materials Science and Engineering, 2020 Conical pick wear is an urgent problem in the roadway excavation caused by hard rock difficult to break. The traditional method of increasing cutting power to improve cutting performance of conical pick significantly increases pick wear.
Zhenguo Lu +4 more
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Meikuang Anquan, 2023 The arched rock bolt support plate is one of the key components in the rock bolting system, and its structural size and strength directly affect the rock bolting effect.
YAN Ruyu, NING Jianguo, ZHANG Zhi, SUN Guoqing, DU Minghao
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Science Progress, 2021 Based on the 16–32 m simply-supported beam bridge on Shanghai-Kunming high-speed railway, a collision model of CRTS II track system was established.
Bin Yan, Zhe Li, Shi Liu, Hao-Ran Xie
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Scientific ReportsA humeral locking plate augmented with fibular strut allograft treated for proximal humeral fracture without internal structural support is satisfactory. While it is better clinically and biomechanically than the locking plate alone, it has disadvantages,
Cheng-Hung Lee +3 more
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