Results 61 to 70 of about 149,652 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A clamping force measurement system for monitoring the condition of bolted joints on railway track joints and points

, 2012
Many industrial structures associated with railway infrastructures rely on a large number of bolted joint connections to ensure safe and reliable operation of the track and trackside furniture.
Gu, Fengshou, Ball, Andrew, Ball, A. D., Horler, Greg, Al Thobiani, F., Horler, G., Gu, F., Al Thobiani, Faisal, Tesfa, Belachew, Tesfa, B.   +9 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Stretchable force sensors [PDF]

The Journal of Cell Biology, 2006
![Graphic][1] Stretching of p130Cas (top) increases its phosphorylation (bottom). SHEETZ/ELSEVIER Cells in the body somehow sense that they are continually being pushed and pulled.
openaire   +1 more source

Technical characteristic analysis and calibration of strain type force transducer in complex working conditions

Measurement: Sensors, 2021
The working condition of force sensor in the field of industrial thrust measurement is complex, which is different from that in the laboratory calibration.
Haifeng Qin, Sibo Liu, He Li
doaj   +1 more source

PIEZO Force Sensors and the Heart

Cold Spring Harbor Perspectives in Biology
The PIEZO1 and PIEZO2 membrane proteins form uniquely structured calcium permeable nonselective cation channels dedicated to mechanical force sensing in eukaryotic cells. In this review of the scientific literature, we address PIEZOs in the heart. PIEZOs enable the formation of the aortic valve, cardiac vasculature, and pericardial drainage.
McGrane, A., Murray, M., Bartoli, F., Giannoudi, M., Conning-Rowland, M., Stewart, L., Levelt, E., Cubbon, R.M., Dall'Armellina, E., Griffin, K.J., Herum, K.M., Smith, A.J., Beech, D.J.   +12 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Estimation of coefficient of static friction with one-axis force sensor by observing peripheral local slips on elastic hemisphere

SICE Journal of Control, Measurement, and System Integration, 2021
With the development of aging societies, medical costs due to slip-related-falls (SRFs) continue to increase. In order to monitor the accidents, wearable shoe systems to detect slips are promising tools to prevent SRFs in daily activities.
Yusaku Tagawa, Taiyu Okatani, Hiroshi Onodera   +2 more
doaj   +1 more source

Characterisation of PZT thin film micro-actuators using a silicon micro-force sensor [PDF]

, 2007
This paper reports on the measurements of displacement and blocking force of piezoelectric micro-cantilevers. The free displacement was studied using a surface profiler and a laser vibrometer.
Ensell, Graham, Wilson, Stephen, Duval, Fabrice, Duval, Fabrice F. C., Whatmore, Roger, Cain, Markys, Wilson, Stephen A., Whatmore, Roger W., Evanno, Nicolas M. P., Evanno, Nicolas, Cain, Markys G.   +10 more
core   +1 more source