Results 91 to 100 of about 316,009 (304)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Small influence of solar variability on climate over the past millennium [PDF]
, 2014 The climate of the past millennium was marked by substantial decadal and centennial scale variability in the Northern Hemisphere(1). Low solar activity has been linked to cooling during the Little Ice Age (AD 1450-1850; ref.
Hegerl, Gabriele C. +5 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Efficacies of various forcing components contributing to aircraft climate impact [PDF]
, 2013 The net impact of aviation on global climate results from a combination of individual contributions (e.g. from CO2, ozone, and methane changes, contrails).
Ponater, Michael
core
A multispecies perspective on ecological impacts of climatic forcing [PDF]
, 2010 P>1. In the prevailing context of concerns over climate change and its potential impacts on ecosystems, evaluating ecological consequences of climatic forcing has become a critical issue. 2.
O'hara, R. B. +5 more
core +1 more source
Topology and models of ZFC at early Universe
Zagadnienia Filozoficzne w Nauce, 2019 Recently the cosmological evolution of the universe has been considered where 3-dimensional spatial topology undergone drastic changes. The process can explain, among others, the observed smallness of the neutrino masses and the speed of inflation ...
Jerzy Król, Torsten Asselmeyer-Maluga
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source