Results 91 to 100 of about 114,734 (298)
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]
, 2007 Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
Richardson, WD +3 more
core
A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability
Advanced Science, EarlyView.The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang +17 more
wiley +1 more source
Advanced Science, EarlyView.Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland +4 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo +2 more
wiley +1 more source
Redescription of the Triassic cynodont Cistecynodon parvus and reassessment of its phylogeny
The Anatomical Record, EarlyView.Abstract Cynodontia is an important subclade of Therapsida that first occurred in the late Permian. It includes extinct subclades which are the non‐mammaliaform cynodonts and Mammaliaformes, with the latter ultimately giving rise to crown mammals. The systematics of non‐mammaliaform cynodonts has been extensively studied and is relatively well‐resolved,
Erin S. Lund +4 more
wiley +1 more source
E-Cadherin regulates neural stem cell self-renewal
, 2009 E-Cadherin, a cell adhesion protein, has been shown to take part in the compartmentalization, proliferation, survival, and differentiation of cells.
DeVeale, B. +5 more
core +1 more source
Exceptional preservation informs the paleobiology of tapinocephalid dinocephalians
The Anatomical Record, EarlyView.Abstract The tapinocephalid dinocephalian Moschops is one of the most iconic taxa of the middle Permian, yet its paleobiology remains one of the least well‐known. Here, we address some aspects of paleoneurology and paleobiology of Moschops using CT scanning of four well preserved skulls from the upper Abrahamskraal Formation of South Africa. Two of the
Julien Benoit +6 more
wiley +1 more source