Results 121 to 130 of about 81,679 (340)

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

open access: yesDrug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke   +4 more
wiley   +1 more source

Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series

open access: yesJournal of Translational Medicine
Background The tumor-agnostic indication of immune checkpoint inhibitors to treat cancers with mismatch repair deficiency (dMMR)/microsatellite instability (MSI) increased the demand for such tests beyond Lynch syndrome.
Maja L. Nádorvári   +6 more
doaj   +1 more source

Forensic Pathology [PDF]

open access: green, 1997
PR Pathak
openalex   +1 more source

Estimation of Plasma Volume by Machine Learning to Improve the Interpretation of the Athlete Biological Passport

open access: yesDrug Testing and Analysis, EarlyView.
A new machine learning model for plasma volume (PV) estimation was applied within the ABP framework. PV estimation was applied through visual displays or corrected ABP thresholds. With a favorable assessment from ABP experts, these results support further application of this model in the presence of specific confounding factors.
Bastien Krumm   +6 more
wiley   +1 more source

mRNA Biomarkers in Dried Blood Spots May Improve Detection of Autologous Blood Micro‐Transfusions Using an Individualized Approach

open access: yesDrug Testing and Analysis, EarlyView.
This study shows that measuring ALAS2 mRNA expression from dried blood spots (DBS) can sensitively identify autologous blood micro‐transfusions (ABMTs) ABMTs with > 95% sensitivity and specificity through individualized analysis. These results highlight ALAS2 mRNA in DBS as a promising tool to strengthen anti‐doping efforts against small‐volume ...
Andreas Breenfeldt Andersen   +7 more
wiley   +1 more source

Gut microbiota modulates depressive-like behaviors induced by chronic ethanol exposure through short-chain fatty acids

open access: yesJournal of Neuroinflammation
Background Chronic ethanol exposure (CEE) is recognized as an important risk factor for depression, and the gut-brain axis has emerged as a key mechanism underlying chronic ethanol exposure-induced anxiety and depression-like behaviors. Short-chain fatty
Hui Shen   +15 more
doaj   +1 more source

Home - About - Disclaimer - Privacy