Results 121 to 130 of about 216,058 (206)

Expression of Drosophila forkhead transcription factors during kidney development. [PDF]

open access: yesBiochem Biophys Res Commun, 2014
Baek JI   +4 more
europepmc   +1 more source

Cisplatin‐Induced Muscle Wasting and Atrophy: Molecular Mechanism and Potential Therapeutic Interventions

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Platinum‐based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects. However, a significant side effect of cisplatin is muscle atrophy, which severely impairs physical strength, diminishes quality of life and complicates cancer therapy.
Ko‐Chieh Huang   +3 more
wiley   +1 more source

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

open access: yesJOR SPINE, Volume 8, Issue 2, June 2025.
Within this manuscript, bioinformatics and experimental methods are used to explore the role of circadian rhythm and immunity in Intervertebral Disc Degeneration (IVDD). CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI were successfully demonstrated to be hub rhythm‐related genes in the process of IVDD together with immunity.
Yongbo Zhang   +5 more
wiley   +1 more source

DNA-binding specificity changes in the evolution of forkhead transcription factors. [PDF]

open access: yesProc Natl Acad Sci U S A, 2013
Nakagawa S   +4 more
europepmc   +1 more source

Targeting the Enhanced Sensitivity of Radiotherapy in Cancer: Mechanisms, Applications, and Challenges

open access: yesMedComm, Volume 6, Issue 6, June 2025.
In this review, we first introduced the current application scenarios for radiotherapy in tumor treatment, the molecular mechanisms underlying anticancer effects of radiotherapy in treatment of cancer, and the side‐effects of radiotherapy. Second, we pay attention to discuss the main types of radiosensitizers and their latest applications and ...
Yuanyuan Zhao   +5 more
wiley   +1 more source

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