Results 301 to 310 of about 626,933 (316)

Forkhead box-O transcription factor: critical conductors of cancer's fate

Endocrine Related Cancer, 2008
Cells have evolved elaborated mechanisms to coordinate the cellular answer of either survival or apoptosis. Recent concepts of human carcinogenesis have suggested disturbances in these cellular relays as a potential link to cellular dedifferentiation and uncontrolled proliferation.
Weidinger, Carl, Krause, Kerstin, Klagge, Antje, Karger, Stefan, Führer, Dagmar   +4 more
openaire   +3 more sources

Pathophysiological Relevance of Forkhead Transcription Factors in Brain Ischemia

2009
Forkhead box transcription factor, class 0 (FOXO) is a mammalian homologue of DAF-16, which is known to regulate the lifespan of Caenorhabditis elegans and includes subfamiies of forkhead transcription factors such as FOXO1 (FKHR). FOXO3 (FKHRL1), FOXO4 (AFX) and FOXO6.
Kohji, Fukunaga, Norifumi, Shioda
openaire   +2 more sources

FOXO transcription factors as mediators of stress adaptation

Nature reviews. Molecular cell biology, 2023
M. Rodríguez-Colman, T. Dansen, Boudewijn M. T. Burgering   +2 more
semanticscholar   +1 more source

Forkhead Box O Transcription Factors: Key Players in Redox Signaling

Antioxidants & Redox Signaling, 2011
The Forkhead Box O (FOXO) transcription factors are famous for their role in longevity: both Caenorhabditis elegans and Drosophila melanogaster can extend their median and maximum lifespan in a FOXO-dependent manner, and certain single nucleotide polymorphisms in human FOXO genes are associated with reaching an age above 100 years.
openaire   +3 more sources

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

Nature, 2000
R. Medema, G. Kops, J. Bos, B. Burgering
semanticscholar   +1 more source

Transcription Factors: Forkhead Box (FOX)

2022
Vladimir V. Kalinichenko, Craig S. Bolte, Tanya V. Kalin   +2 more
openaire   +1 more source

Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis

Nature reviews. Immunology, 2018
D. Zaiss, P. Coffer
semanticscholar   +1 more source

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin.

Biochimica et Biophysica Acta - General Subjects, 2017
Dimitrios Tsitsipatis, L. Klotz, H. Steinbrenner   +2 more
semanticscholar   +1 more source

Forkhead box transcription factors in embryonic heart development and congenital heart disease.

Life Science, 2016
Hong Zhu
semanticscholar   +1 more source

Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

Science, 2004
A. Brunet, Lora B. Sweeney, J. Sturgill, Katrin F. Chua, P. Greer, Yingxi Lin, Hien G. Tran, S. E. Ross, R. Mostoslavsky, H. Cohen, Linda S. Hu, Hwei-Ling Cheng, Mark P. Jedrychowski, S. Gygi, D. Sinclair, F. Alt, M. Greenberg   +16 more
semanticscholar   +1 more source