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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Effect of recycling on the mechanical properties and formability of sheet metal [PDF]
This technical note analyses the effect of recycling on the mechanical and forming behaviour of two aluminium alloys (5xxx and 6xxx series) and a low-carbon high-formability steel grade, three of the most widely used sheet metal products in various ...
Payá Anna +3 more
doaj +1 more source
Prediction of the mechanical behaviour of TRIP steel [PDF]
TRIP steel typically contains four different phases, ferrite, bainite, austenite and martensite. During deformation the metastable retained austenite tends to transform to stable martensite.
Geijselaers, H.J.M., Perdahcioglu, E.S.
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Investigating the Effect of Rotation Speed and Ultrasonic Vibrations in the Incremental Forming Process [PDF]
Incremental forming is one of the forming methods that is considered because of no need to specific die, especially for rapid prototyping. In this study, the incremental forming process is carried out by using a rotating tool and assisted ultrasonic ...
Saeed Amini +3 more
doaj
A Dislocation based Constitutive Model for Warm Forming of Aluminum Sheet [PDF]
The formability of aluminum sheet can be improved considerably by increasing the temperature.\ud At elevated temperatures, the mechanical response of the material becomes strain rate dependent.\ud To accurately simulate warm forming of aluminum sheet, a ...
Boogaard, A.H. van den +2 more
core +1 more source
Tidal deformability from GW170817 as a direct probe of the neutron star radius
Gravitational waves from the coalescence of two neutron stars were recently detected for the first time by the LIGO-Virgo collaboration, in event GW170817. This detection placed an upper limit on the effective tidal deformability of the two neutron stars
Psaltis, Dimitrios +2 more
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
In this study, the compositional design of high-formability, high-bake-hardening Al–Mg–Zn-Cu-based aluminum alloys was carried out, and process conditions were established to secure mechanical properties under harsh conditions for Al–Mg–Zn-Cu-based ...
GyeongSeok Joo +4 more
doaj +1 more source

