Results 61 to 70 of about 674,793 (310)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Non-formal education between formal and informal education

open access: yes, 2021
This article addresses the issue of non-formal education from different perspectives: conceptual, content-related, organizational. Attention is drawn to the comparison of formal, non-formal and informal education, the peculiarities and functions of non-formal education and the development trends of this subsystem of education are established.
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Formal Education and New Openings For Self-Employment Amongst Foreign-Born Persons in the Swedish Healthcare Sector

open access: yesNordic Journal of Migration Research, 2017
This study contributes to the discussion on the value of education for self-employment among foreign-born persons in Sweden. The case of the deregulated healthcare sector is used to illustrate the importance of the acknowledgement of unaccustomed types ...
Susanne Urban, Tobias Schölin
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Intrinsic and extrinsic factors influencing student well-being and their relationship to academic well-being

open access: yesDiscover Psychology
Student well-being has become a central issue in higher education as universities confront rising concerns about academic stress, mental health, and student resilience.
Diana Rahmasari   +4 more
doaj   +1 more source

Psychologist in non-formal education [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2011
Learning is not limited to school time. It starts at birth and continues throughout the entire life. Equally important as formal education there are also non-formal and informal education. Any kind of learning outside the traditional school can be called
Pavićević Miljana S.
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

EDUCAȚIA NONFORMALĂ ÎN CADRUL UNIVERSITAR DIN PERSPECTIVA REALIZĂRII INTERCONEXIUNII ȘI CONTINUITĂȚII ÎNTRE CICLURI DE ÎNVĂȚĂMÂNT SUPERIOR

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei, 2019
În articol este abordată problema educației nonformale (extracurriculare) din perspectiva realizării interconexiunii și continuității între cicluri de învățământ superior.
Tatiana REPIDA, Carolina ȚURCANU
doaj  

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