Results 151 to 160 of about 449,052 (266)

Utility of Fine Needle Aspiration Supernatant for Real-Time PCR-Based Mutation Analysis in Non-Small Cell Lung Cancer. [PDF]

Diagn Cytopathol
Akinsanya A, Gorden R, Rector M, Muhammad H, Randolph M, Sperling M, Xu K, Segura S, Saeed O, Hou T.   +9 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Ramipril and Olmesartan: Unveiling their pleiotropic potential as immunomodulators. [PDF]

Indian J Pharmacol
Dasan J, Yesunesan A, Chandran V, Mathew J, Mathew L.   +4 more
europepmc   +1 more source

Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting

Advanced Science, EarlyView.
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family, Aneela Davuluri, Athulya Martin, Kyungsuk Yum   +3 more
wiley   +1 more source

Involvement of the Opioid Pathway in the Antinociceptive Activity of the Aqueous Stem Extract from <i>Doyerea emetocathartica</i>. [PDF]

Pharmaceutics
de Oliveira GD, Araújo MML, da Silva PCD, de Sousa GR, de Moraes MF, Costa WK, Dos Santos Correia MT, de Oliveira AM, Cibulski SP, da Silva Alves H.   +9 more
europepmc   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Antinociceptive and Anti-Inflammatory Effects of Syringic Acid: <i>In Vivo</i> Evidence and <i>In Silico</i> Mechanistic Insights. [PDF]

ACS Omega
Yön Ş, Yazıcı Şenocak C, Türkoğlu Sağlık G, Kandemir Ü, Eser M, Evren AE, Can ÖD, Demir Özkay Ü.   +7 more
europepmc   +1 more source

Formalin as a Preservative [PDF]

Nature, 1899
openaire   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Extracellular Particles Isolated from Leftover Discarded Formalin-Fixed Tissues Exhibit Atypical Extracellular RNA Profiles. [PDF]

Biomolecules
Tallapaneni V, Okeoma BC, Sachidanandam R, Islam HK, Okeoma CM.   +4 more
europepmc   +1 more source