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Distal resection margins before and after fixation: a comparative analysis in rectal cancer surgery. [PDF]
Front SurgEdizsoy A +4 more
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Advanced Science, EarlyView.Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang +11 more
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The functional role of opioidergic system within the ventral tegmental area and the dentate gyrus of hippocampus in modulation of the persistent inflammatory pain in the rats. [PDF]
IBRO Neurosci RepSaghafi M, Azizbeigi R, Haghparast A.
europepmc +1 more source
Integrative GC-MS, FT-IR, and Molecular Docking Analysis of <i>Drimycarpus racemosus</i> (Roxb.) Hook.f ex Marchand: In Vivo Analgesic and Antidiabetic Potential. [PDF]
Food Sci NutrAli MS +7 more
europepmc +1 more source
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The interphase of the formalin test
Pain, 2014The formalin test still surprises with its biphasic pain-related behavior resulting from a quiescent interphase that does not occur with other algogenic compounds and remains unexplained. The first phase has been attributed to TRPA1-mediated excitation of nociceptors, the second phase to their inflammatory and/or spinal sensitization.
Michael, Fischer +3 more
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Neuroscience & Biobehavioral Reviews, 2004
The subcutaneous injection of formalin into the rat upper lip generates behavioral responses that last several minutes. The time course of the response is similar to what is observed following formalin injection into the paw, i.e. biphasic, with an early and short-lasting first phase followed, after a quiescent period by a second, prolonged (tonic ...
Patrick, Raboisson, Radhouane, Dallel
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The subcutaneous injection of formalin into the rat upper lip generates behavioral responses that last several minutes. The time course of the response is similar to what is observed following formalin injection into the paw, i.e. biphasic, with an early and short-lasting first phase followed, after a quiescent period by a second, prolonged (tonic ...
Patrick, Raboisson, Radhouane, Dallel
openaire +2 more sources
The formalin test in mice: effect of formalin concentration
Pain, 1990The effect of different formalin concentrations on the nociceptive response in the formalin test was examined in mice. Subcutaneous formalin injection induces 2 distinct periods of high licking activity: an early phase lasting the first 5 min, and a late phase lasting 20-30 min after the injection.
Jan Henrik, Rosland +3 more
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