Results 141 to 150 of about 18,671,672 (383)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Simulations of the formation, evolution and clustering of galaxies and quasars

open access: yesNature, 2005
V. Springel   +16 more
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

La liberté spatiotemporelle comme facteur d’engagement des étudiants? Étude de deux cas (peut être pas si uniques)

open access: yesRevue internationale des technologies en pédagogie universitaire, 2020
Christophe Gremion   +2 more
doaj   +1 more source

Collagen fibril formation. Optimal in vitro conditions and preliminary kinetic results.

open access: hybrid, 1978
Benfeard Williams   +3 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Formation of Galaxy Disks

open access: yes, 2008
We present a new set of multi-million particle SPH simulations of the formation of disk dominated galaxies in a cosmological context. Some of these galaxies are higher resolution versions of the models already described in Governato et al (2007).
Brook, C., Governato, F., Mayer, L.
core  

Home - About - Disclaimer - Privacy