Results 51 to 60 of about 806,605 (263)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Bilan de pratiques évaluatives des apprentissages à distance en contexte de formation universitaire
Revue Internationale de Pédagogie de l’Enseignement Supérieur, 2016 The development of distance learning in higher education raises the question of the nature and validity of evaluation practices of teachers in a context where the nature of the collected data, the scope and credibility of their interpretation and the ...
Isabelle Nizet +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Formation à distance et activité du stagiaire de la formation professionnelle continue
Éducation et Socialisation, 2014 This paper discusses the practical vocational training in the framework of a hybrid system. This is particularly ask the vocationnal education training as operational content to facilitate the transformation of subjects in action.
Béatrice Verquin-Savarieau
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Quelques incontournables de la formation à distance [PDF]
, 2022 Bien que la formation à distance existe de longue date, la plupart des acteurs de l’éducation ont rencontré des difficultés à passer de la présence à la distance lorsque les mesures sanitaires l’exigeaient.
Papi, Cathia
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Analyse de Penser la mise à distance en formation
ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2000 This article reviews a book or document.
Anne-Laure Foucher
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Formation à distance et hybridation [PDF]
, 2013 L’intégralité de cet entretien est disponible en libre accès sur Internet à l’adresse suivante : http://www.ife.ens-lyon.fr/publications/edition-electronique/recherche-et-formation/RR068-9.pdf.
Manderscheid, Jean-Claude +1 more
core +1 more source