Results 41 to 50 of about 797,920 (217)
Le numérique, pour coopérer en formation à distance
Communication, Technologies et Développement, 2018 In a research project conducted in four educational institutions, we addressed the following question: How does digital technology enhance or limit cooperation between the design and management teams? From 44 individual interviews and 8 group interviews,
Nicole Racette +1 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
La formation professionnelle à distance à la lumière des organisations capacitantes
Distances et Médiations des Savoirs, 2016 Professional training is concerned by the digitalization of enterprises, a process which refers to the massive use of new technologies. After the popularity of e-learning, the environments inspired by the academic MOOC (COOC, SPOC etc.) appeared to many ...
Anca Boboc, Jean-Luc Metzger
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Bilan de pratiques évaluatives des apprentissages à distance en contexte de formation universitaire
Revue Internationale de Pédagogie de l’Enseignement Supérieur, 2016 The development of distance learning in higher education raises the question of the nature and validity of evaluation practices of teachers in a context where the nature of the collected data, the scope and credibility of their interpretation and the ...
Isabelle Nizet +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Formation à distance et activité du stagiaire de la formation professionnelle continue
Éducation et Socialisation, 2014 This paper discusses the practical vocational training in the framework of a hybrid system. This is particularly ask the vocationnal education training as operational content to facilitate the transformation of subjects in action.
Béatrice Verquin-Savarieau
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source