Results 41 to 50 of about 2,929,313 (259)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

In The Neighbourhood of Tame Monsters: A study of galaxies near low-redshift quasars

, 2012
The impact of quasars on their galaxy neighbours is an important factor in the understanding of galaxy evolution models. The aim of this work is to characterize the intermediate-scale environments of quasars at low redshift (z $
Abazajian, Aihara, Almeida, Arnol, B. Villarroel, Babul, Baldwin, Barnes, Barnes, Bergvall, Bergvall, Boroson, Brinchmann, Bushouse, Canalizo, Canalizo, Charlot, Cho, Coldwell, Connolly, Donzelli, Efron, Ellison, Gehren, Grcevich, Gunn, Hao, Hopkins, Hopkins, Hutchings, Kauffmann, Kennefick, Kennicutt, Kewley, Kewley, Lamastra, Li, Lietzen, Lintott, Lintott, Lintott, Liu, Lynden-Bell, Martig, Moustakas, Nikolic, Park, Petrosian, Press, Raimann, Raymond, Rees, Reyes, Rogers, Scannapieco, Schmidt, Schneider, Schneider, Schneider, Searle, Serber, Shen, Shields, Sijacki, Silk, Stoughton, Strand, Strateva, Strauss, Sutherland, Tabor, Toomre, Way, Way, Whitford, Yee, Yin, York   +77 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Perspectives actuelles sur la formation à l’ère du numérique

Médiations & Médiatisations, 2023
Ce numéro compte trois articles de recherche, un article de praticiens et deux articles de discussions et débats offrant une exploration de divers sujets au cœur de la technologie éducative.
Gustavo Adolfo Angulo Mendoza, Cathia Papi   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comment on "Are periodic solar wind number density structures formed in the solar corona?" by N. M. Viall et al., 2009, Geophys. Res. Lett., 36, L23102, doi:10.1029/2009GL041191

, 2010
Location of formation of periodic solar wind number density structures is discussed. Observation of proton and alpha anticorrelation in these structures [Viall et al., 2009] indicates that taking into account that bulk velocity of aplha-particles is ...
D Bollea, DE Robbins, E Marsch, JM Bosqued, JR Asbridge, KW Ogilvie, KW Ogilvie, L Kepko, L Kepko, LM Zelenyi, M Neugebauer, NM Viall, V Formisano, Y Yamauchi, Yu. I. Yermolaev, YuI Yermolaev, YuI Yermolaev   +16 more
core   +1 more source

Bearing-based formation control with second-order agent dynamics [PDF]

, 2018
We consider the distributed formation control problem for a network of agents using visual measurements. We propose solutions that are based on bearing (and optionally distance) measurements, and agents with double integrator dynamics.
Tron, Roberto
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Des institutions dédiées à la formation à distance : passé ou futur de l’éducation ?

Médiations & Médiatisations, 2021
Cette introduction à la rubrique « Témoignages et entretiens » propose une lecture transversale des cinq entretiens qui la composent et présentent des institutions renommées dédiées à la formation à distance.
Cathia Papi, Viviane Glikman, Hélène Pulker   +2 more
doaj   +1 more source