Results 181 to 190 of about 2,239,947 (297)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Nutritional Intervention and Physical Activity in Adolescents and Children with Obesity. [PDF]
NutrientsRomero-Blanco C, Aznar S.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tea-derived catalysts: a sustainable approach to organic transformations. [PDF]
RSC AdvAmiri M, Vazehi Z, Abedini M, Shirini F.
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Microstructure Evolution and Damage Mechanism of DD9 Single Crystal Superalloy-Thermal Barrier Coating System Under High Temperature Oxidation: A Comparative Study with DD6. [PDF]
Materials (Basel)Li P, Xin Z, Sun F, Jin X, Zhang C.
europepmc +1 more source
Formation continue au service des bibliothèques de 1976 à 1980 (La) [PDF]
Marchizet, Marie-Noëlle +1 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Injection Molding and Special Injection Molding Technologies of Polymer and Polymer Composites. [PDF]
Polymers (Basel)Wang J.
europepmc +1 more source