Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
A Case of Common Iliac Artery Pseudoaneurysm Formation, Rupture, and Rectal Fistula Caused by <i>Escherichia coli</i>. [PDF]
Clin Case RepZhao X, Zhang L, Liu A.
europepmc +1 more source
Dotation du personnel enseignant à l'enseignement régulier et à la formation continue [PDF]
, 2007 core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Optimizing postoperative inflammation in pediatric cataract surgery: Are intracameral steroids the way forward? [PDF]
Indian J OphthalmolMurali K +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Programme d'évaluation du personnel enseignant du Service de la formation continue du cégep Saint-Jean-sur-Richelieu [PDF]
, 2004 core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Exploring Both In-Depth Theories of Disorders and the Current State of Child and Adolescent Mental Health at the Same Time. [PDF]
J Korean Acad Child Adolesc PsychiatrySon JW.
europepmc +1 more source