Results 141 to 150 of about 2,251,358 (297)
Formation continue en jonglerie
Le premier auteur est étudiant passionné de jonglerie, il a réalisé un mémoire de fin d’études portant sur l’utilisation de la jonglerie en milieu scolaire. Cet article est préparé à partir du contenu de formations continuées proposées aux maîtres de stage qui collaborent à la formation des étudiants de l’AESS de l’Institut Supérieur d’Education ...
Fischbach, Willi, Cloes, Marc
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Catalyzing collaboration through intentional design: the Teaming for Biomedical Digital Twin (Teaming4BDT) conference. [PDF]
Bennett LM, Xiao Z.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Celebrating the 30th Anniversary Year of the Founding of <i>The Permanente Journal</i>. [PDF]
Holt GR.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

