Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
AI in Lung Nodules on Chest CT: Retrospective, Real-World Assessment of AI in Clinical Practice. [PDF]
Sodhi-Kalra H, Jha S, Digumarthy S.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Fixed Versus Lottery Incentives for Promoting Engagement With a Cadence-Based Smartphone App: Randomized Crossover Trial. [PDF]
Hayashi K +9 more
europepmc +1 more source
Analysis on suicide risk in medical students, an analysis based on socio-formative conceptual mapping. [PDF]
Calles-Santoyo ME +3 more
europepmc +1 more source
Strengthening Indigenous community engagement in clinical research: a formative evaluation in Northern British Columbia. [PDF]
Campos Clímaco J +4 more
europepmc +1 more source
Serious Game Aimed at Assessing Executive Planning Skills in Children With Autism: Cross-Sectional Design and Formative Evaluation of ShopAutiPlan. [PDF]
Shamhan ANM +3 more
europepmc +1 more source
Experiences of stigma and violence among persons affected by skin neglected tropical diseases (NTDs): longitudinal analysis from an integrated intervention in Liberia. [PDF]
Hotopf I +15 more
europepmc +1 more source

