The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Enhancing peer teaching and psychological outcomes in medical education through structured formative assessment: a quasi-experimental study. [PDF]
Zhang D +8 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Implementation of DOPS (Direct Observation of Procedural Skills) as formative assessment tool to enhance procedural skills in anesthesia postgraduate students. [PDF]
Gupta N, Saxena D, Malviya S.
europepmc +1 more source
Introduction of Formative Assessment Classroom Techniques (FACTs) to School Chemistry Teaching: Teachers' Attitudes, Beliefs, and Experiences. [PDF]
Babinčáková M +2 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
HIV services for fisherfolk in Sierra Leone: A formative assessment of barriers, opportunities, and community preferences. [PDF]
Zech JM +12 more
europepmc +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
A Formative Assessment System in Baduanjin Physical Education Based on Inertial Measurement Unit Motion Capture. [PDF]
Ma X +6 more
europepmc +1 more source
Wet Laboratory Training in Ophthalmology as a Tool for Formative Assessment. [PDF]
Bhagat PR, Jethva J.
europepmc +1 more source

