Results 151 to 160 of about 46,757 (308)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

A CHAT Analysis: Narrating the Writing Center’s Formative Period from Praxis: A Writing Center Journal Vol. 21 No. 3

open access: yes
From the recognized beginning of the “laboratory” movement in composition instruction, teachers have sought to employ new and more practical methods useful in developing student writing. Such trends continue today as new generations of students enter
Moore, Don
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Physical Violence and Social Tension in the Atacama Desert: Osteobiography of a Woman from the Tarapaca 40 Formative Period Cemetery

open access: yes
Physical violence and social conflict have been widely studied in the ancient societies of the Andes. However, studies about violence are scarce for the Formative period of northern Chile (1000 BC-AD 900).
Gonzalez-Ramirez, Andrea   +7 more
core   +1 more source

Some Notes on the History of the Categorization of Imāmī Ḥadīth

open access: yesTurkish Journal of Shiite Studies, 2019
The formative period of Imāmī law is generally placed in Buwayhid Baghdad. However, by the end of the Buwayhid era, Imāmī law had not yet developed all of the features that would enable future scholars to elaborate the law along particular methodological
Aun Hasan Ali
doaj  

ON PERIODS OF CUSP FORMS

open access: yesMemoirs of the Faculty of Science, Kyushu University. Series A, Mathematics, 1981
openaire   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Contemporary analysis of the Valdivia, a formative period coastal Ecuadorian culture

open access: yes, 2007
The Valdivia culture of coastal Ecuador was a sophisticated Formative Period culture which is best known for being among the earliest ceramic makers in the whole of the Americas. Although it was discovered in 1956 by amateur archaeologist Emilio Estrada,
Peraza, Christopher
core  

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