Results 131 to 140 of about 46,757 (308)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Scientific Expertise and Regulatory Politics in Germany: The Formative Period of Handling Risks by Agreeing on "Acceptable" Standards, 1870–1913

open access: yes, 1997
Lundgreen P. Scientific Expertise and Regulatory Politics in Germany: The Formative Period of Handling Risks by Agreeing on "Acceptable" Standards, 1870–1913. In: Technical Expertise and Public Decisions. Proceedings.
Lundgreen, Peter
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Jan-Olaf Blichfeldt, Early Mahdism. Politics and Religion in the Formative Period of Islam. Studia Orientalia Lundensia, Leiden, Brill, 1985

open access: yes, 1987
Gril Denis. Jan-Olaf Blichfeldt, Early Mahdism. Politics and Religion in the Formative Period of Islam. Studia Orientalia Lundensia, Leiden, Brill, 1985. In: Bulletin critique des annales islamologiques, n°4, 1987. pp.
Gril, Denis
core  

3 Situational Inalienability and Social Change in Formative Period Coastal Oaxaca

open access: yes, 2013
This paper examines the role of caches, burials, and mortuary offerings as forms of inalienable wealth in the lower Río Verde valley of Pacific coastal Oaxaca, Mexico.
Workinger, Andrew   +5 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Beyond the Formative Years

open access: yes, 2017
This chapter offers an outlook on the further transformations of Einstein's theory after the formative years. Following this period, the theory underwent a process of marginalization within the field of physics. Jean Eisenstaedt characterized these years
Hanoch Gutfreund, Jürgen Renn
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Automorphic forms, hyperfunction cohomology, and period functions.

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal), 1997
\textit{J. B. Lewis} [Invent. Math. 127, 271-306 (1997)] has given a relation between cuspidal Maass forms for the full modular group, and holomorphic functions \(\psi\) on \(\mathbb{C}\setminus(- \infty,0]\) that satisfy \[ \psi(z)= \psi(z+ 1)= (z+ 1)\psi\Biggl({z\over z+1}\Biggr).
openaire   +4 more sources

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