Results 141 to 150 of about 5,092,235 (300)
Formative Assessment for mathematics teaching and learning
This book aims at describing pathways and achievements of the LLP Comenius Project “FAMT&L – Formative Assessment in mathematics for teaching and learning”. The main purpose of this research project was to encourage the use of formative assessment in the
Ferretti, Federica +2 more
core
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Word-formation features of the Kazan Gospel of the 14th century: Nominal derivation
The nominal word formation in the text of the Kazan Gospel of the 14th century relating to the lectionaries of the Mstislav type has been analyzed. The study aims to clarify the available data on this issue, to add to the description of the lexical and ...
N.G. Nikolaeva
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Formative assessment in higher education an example from astronomy
This chapter addresses the challenges and potential of implementing formative assessment in higher education with a specific focus on astronomy. We emphasize the use of formative assessment strategies as a coherent whole and a learning environment that ...
Kristianstad University. +2 more
core
El proceso de cambio de una sociedad de pescadores- recolectores,como los grupos Chinchorro, hacia una sociedad agrícola más sedentaria, como se ha planteado para las poblaciones Faldas del Morro y Alto Ramírez, no solo implicó un cambio en la ...
Iván Ricardo Muñoz Ovalle +1 more
doaj
openaire +2 more sources
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

