Results 81 to 90 of about 1,630,631 (307)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Effects of layer arrangement, pin size, polyurethane thickness, and polyurethane hardness on forming limits of Al/Cu bimetallic sheets through multi-point forming process

Journal of Materials Research and Technology
This study experimentally evaluated the forming limit diagram (FLD) of Al/Cu bimetallic sheets fabricated using explosive welding in multi-point forming.
Milad Aali Majidabad, Ramin Hashemi, Habibolah Akbari   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Microwave Power Transmission Workshop summary [PDF]

, 1980
The assumptions, methodologies, and conclusions of the NASA SPS studies were assessed and criticized to identify critical issues and to make recommendations for follow-on works.
Freeman, J. W.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Effect of Process Parameters on the Forming Limit Angle of AA2024 Aluminum Alloy in Belt-Heated Incremental Sheet Forming

Metals
In the belt-heated incremental sheet forming process, the influence of process parameters on the forming limit angle significantly affects the forming accuracy and quality of components.
Zhengyuan Gao, Zhibing Li, Zhengfang Li, Zhiguo An, Pengfei Sun, Zhong Ren, Jiang Li, Yi Zhang, Han Lin, Zhengyang Qiao   +9 more
doaj   +1 more source

Cluster Formation in Protostellar Outflow-Driven Turbulence

, 2005
Most, perhaps all, stars go through a phase of vigorous outflow during formation. We examine, through 3D MHD simulation, the effects of protostellar outflows on cluster formation.
Bontemps S., Fumitaka Nakamura, Knee L. B. G., Motte F., Zhi-Yun Li   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Forming limit of hot-rolled high-strength steels considering sheet thickness effect [PDF]

MATEC Web of Conferences
The forming limit curve (FLC) has been commonly used tool to predict the metal forming cracking in engineering. Whereas, based on the assumption of plane stress state, the formability prediction of thick sheet of hot-rolled high-strength steels is quite ...
Zhang Shi-Hong, Chen Wei-Jin, Chen Shuai-Feng, Song Hong-Wu, Deng Si-Ying   +4 more
doaj   +1 more source

Unsupervised Deep Learning for Advanced Forming Limit Analysis in Sheet Metal: A Tensile Test-Based Approach. [PDF]

Materials (Basel), 2023
Thamm A, Thamm F, Sawodny A, Zeitler S, Merklein M, Maier A.   +5 more
europepmc   +1 more source