Results 91 to 100 of about 612,190 (327)

Prediction of forming limit curve for pure titanium sheet

Transactions of Nonferrous Metals Society of China, 2018
Abstract Commercially pure titanium (CP Ti) has been actively used in the plate heat exchanger due to its light weight, high specific strength, and excellent corrosion resistance. However, researches for the plastic deformation characteristics and press formability of the CP Ti sheet are not much in comparison with automotive steels and aluminum ...
Young-Suk KIM, Bong-Hyun LEE, Seung-Han YANG   +2 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Determination of the forming limit diagram of zinc electro-galvanized steel sheets

Metalurgija, 2012
Forming limit curves (FLC) of deep drawing steel sheets have been determined experimentally and calculated on the base of the material tensile properties following the Hill, Swift, Marciniak-Kuczyński and Sing-Rao methods.
W. Fracz, F. Stachowicz
doaj  

The breakage prediction for hydromechanical deep drawing based on local bifurcation theory [PDF]

, 2019
A criterion of sheet metal localized necking under plane stress was established based on the bifurcation theory and the characteristics theory of differential equation. In order to be capable to incorporate the directional dependence of the plastic strain
Huang, W., Lu, H., Qin, S. J., Yu, H. B.
core  

A Theory of the IMF for Star Formation in Molecular Clouds

, 1996
We present models for the initial mass function (IMF) for stars forming within molecular clouds. These models use the idea that stars determine their own masses through the action of powerful stellar outflows.
Adams, Fred C., Fatuzzo, Marco
core   +2 more sources

Experimental Investigation of Forming Limit Curve for AA5754-O

IOP Conference Series: Materials Science and Engineering, 2018
The Forming Limit Curve (FLC) is a line that is consisted of the major and minor strain pairs for different kinds of strain paths. It is widely adopted for the quantitative description of the sheet metal formability. In this paper, a stand-alone servo-motor apparatus associated with the high-accuracy measurement system was developed, based on which the
W N Yuan, M Wan, X D Wu
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Enhancing/Improving Forming Limit Curve and Fracture Height Predictions in the Single-Point Incremental Forming of Al1050 Sheet Material. [PDF]

Materials (Basel), 2023
Hoang TK, Luyen TT, Nguyen DT.
europepmc   +1 more source