Results 81 to 90 of about 2,936,466 (288)
Curve under construction, 2006
, 2006 Curve begins to take shape, with the Exchange Buildings visible in the background.
Hyde, Colin;
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Advances in Mechanical Engineering, 2018 In this study, to estimate the forming limit curves of a steel DP350 sheet, a combination of the finite element method simulation and experimental methods was adopted using the fracture height of experimental specimens and the corresponding in-plane ...
Thi-Bich Mac +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Influence of strategy of evaluation on forming limit curve
, 2013 The forming limit curve is to this day the proven and established method for determining the failure limit of the material and can be used as input parameters for most modern simulation codes in sheet metal forming The quality of the FLC is decisively ...
Kuppert, Andreas; Merklein, Marion; Friebe, Harald; Moller, Theodor; Hotz, Walter; Volk, Wolfram
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Prediction of forming limit curve for pure titanium sheet
Transactions of Nonferrous Metals Society of China, 2018 Abstract Commercially pure titanium (CP Ti) has been actively used in the plate heat exchanger due to its light weight, high specific strength, and excellent corrosion resistance. However, researches for the plastic deformation characteristics and press formability of the CP Ti sheet are not much in comparison with automotive steels and aluminum ...
Young-Suk KIM +2 more
openaire +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A biaxial test for rheological and formability identification
EPJ Web of Conferences, 2010 Accurate constitutive laws and formability limits of materials are essential for a numerical optimization of sheet forming processes. The main objective of this work is to develop a new experimental device able to give for a unique specimen a good ...
Ragneau E. +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source