Results 61 to 70 of about 1,062 (237)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Failure analysis based on microvoid growth for sheet metal during uniaxial and biaxial tensile tests [PDF]
The aim of the presented investigations is to perform an analysis of fracture and instability during simple and complex load testing by addressing the influence of ductile damage evolution in necking processes.
Abbassi, Fethi +2 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Effects of Anisotropic Yield Functions on Prediction of Forming Limit Diagrams of DP600 Advanced High Strength Steel [PDF]
In recent years, numerous researchers have reported that the predicted forming limit diagrams strongly depend on the method of determining the material parameters used in the yield functions and the corresponding the shape of the yield surface.
Ozturk, Fahrettin +2 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
In recent decades, the automotive industry has faced challenges around improving energy efficiency, reducing pollutant emissions, increasing occupant safety, and reducing production costs.
Rafael Guetter Bohatch +4 more
doaj +1 more source
Formulation of Forming Load in V-Bending
A novel method is described to calculate the forming load in V-bending by a press brake. The data of forming load are collected by FEM analysis. With an increase of the punch stroke in V-bending, the forming load increases gradually after the elastic ...
Koumura Yuki, Wang Zhigang
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The experimental determination of Forming Limit Curves, standardized by ISO 12004-2 and ASTM E2218, remains the conventional framework for evaluating sheet metal formability, whereas the Small Punch Test, supported by ASTM E3205, has traditionally ...
Erik López Vargas +8 more
doaj +1 more source

