Results 131 to 140 of about 612,190 (327)

A Review on Sheet Metal Forming Behavior in High-Strength Steels and the Use of Numerical Simulations

Metals
High-strength steels such as Dual Phase (DP), Transformation-Induced Plasticity (TRIP), and Twinning-Induced Plasticity (TWIP) steels have gained importance in automotive applications due to the potential for weight reduction and increased performance in
Luis Fernando Folle, Tiago Nunes Lima, Matheus Passos Sarmento Santos, Bruna Callegari, Bruno Caetano dos Santos Silva, Luiz Gustavo Souza Zamorano, Rodrigo Santiago Coelho   +6 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Forming limit curves for quasi-static and dynamic working-media-based forming processes

, 2018
The production of complex, multi-functional, high-strength components is becoming increasingly important in the sheet metal industry. Especially with small batch sizes, quasi-static working-media-based forming processes (WMF), such as hydromechanical deep drawing (HMD) or high-pressure sheet metal forming (HPF), can be advantageous.
Djakow, E., Homberg, W., Springer, R.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Fracture forming limit curve prediction by ductile fracture models

Procedia Structural Integrity
The fracture forming limit curve is an essential tool giving information about fracture initiation in metal forming applications. In order to obtain a fracture-forming limit curve, the Nakajima test should be carried out. However, these tests are costly and time-consuming processes.
Aksen, Toros Arda, sener, Bora, Esener, Emre, Kocabiçak, Ümit, Firat, Mehmet   +4 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Application of artificial neural networks for characterisation of formability properties of sheet metals

International Journal of Lightweight Materials and Manufacture
Artificial neural network models were developed to estimate forming limit diagrams from tensile test results based on our own experiments and data from the literature for steel and aluminium sheet metals.
Imre Czinege, Dóra Harangozó
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Predicting the fracture forming limit of 5754-O aluminum alloy by finite element simulation

Materials Research Express
Aluminum alloy has the advantages of low specific gravity, easy processing and good welding performance, so it is widely used on automobiles to achieve lightweighting.
Bin Yan, Guocheng Zhang, Xiaoli Liu, Xiaolin Yin   +3 more
doaj   +1 more source

Impact of Uniaxial Pre-Strains on the Forming Limit Curve (FLC) of CuZn 70-30 Brass Sheets for Enhanced Formability in Production Applications Using the Nakajima Test

Journal of Manufacturing and Materials Processing
Brass sheets are extensively utilized in the automotive, electrical, and other industries, where an in-depth understanding of their formability is crucial for achieving optimal performance in production applications. This study investigates the influence
Aseel Hamad Abed, Raed R. Shwaish, Asaad Ali Abbas, Baha S. Mahdi, Waleed Ahmed   +4 more
doaj   +1 more source