Results 81 to 90 of about 21,677 (267)

Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT

International Journal of COPD, 2019
Anthony D D’Urzo,1 Dave Singh,2 James F Donohue,3 Edward M Kerwin,4 Anna Ribera,5 Eduard Molins,5 Ferran Chuecos,5 Diana Jarreta,5 Esther Garcia Gil5 1Department of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto,
D'Urzo AD, Singh D, Donohue JF, Kerwin EM, Ribera A, Molins E, Chuecos F, Jarreta D, Garcia Gil E   +8 more
doaj  

Pharmacoeconomic aspects of bronchial asthma therapy: real clinical practice

Медицинский совет, 2018
According to official statistics, over 1.5 million people have BA in the Russian Federation. Direct costs associated with the treatment of BA in the Russian Federation amount to 8.5 billion rubles.
A. S. Belevsky, A. A. Zaitsev
doaj   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Is ‘GOLD’ standard for the management of COPD in clinical practice?

Drugs in Context, 2012
Summary: primary therapy for chronic obstructive pulmonary disease (COPD) is the removal of the toxic agent (in most cases, tobacco smoke). Additional therapy includes bronchodilators.
Barbara Yawn
doaj   +1 more source

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +3 more sources

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]

, 2019
Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core   +1 more source

Comparing the immediate Bronchodilatory effects of Salbutamol versus Formoterol: A General Practice Study in Patients with Moderate Asthma

South African Family Practice, 2001
Objectives: To determine whether there is significant difference in the onset of bronchodilatory action between salbutamol, a short-acting beta-2 stimulant and formoterol, a long-acting beta-2 stimulant.
C.M. Kruger
doaj   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Tiotropium Add-On and Treatable Traits in Asthma-COPD Overlap: A Real-World Pilot Study

Journal of Asthma and Allergy, 2022
Yoshihisa Ishiura,1 Masaki Fujimura,2 Noriyuki Ohkura,3 Johsuke Hara,3 Kahori Nakahama,1 Yusuke Sawai,1 Takeshi Tamaki,1 Ryuta Murai,1 Toshiki Shimizu,1 Naoyuki Miyashita,1 Shosaku Nomura1 1First Department of Internal Medicine, Kansai Medical University,
Ishiura Y, Fujimura M, Ohkura N, Hara J, Nakahama K, Sawai Y, Tamaki T, Murai R, Shimizu T, Miyashita N, Nomura S   +10 more
doaj  

Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study

Respiratory Research, 2006
Background The long-acting β2-agonist (LABA) formoterol has an onset of effect comparable to that of salbutamol. Consequently, the combination of formoterol and budesonide in one inhaler, approved for maintenance use, can potentially be used for reliever
Bantje Theo A, Jonkers René E, Aalbers René   +2 more
doaj   +1 more source