Results 51 to 60 of about 20,705 (157)

Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations. A real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation [PDF]

, 2011
Background Although patients have more problems using metered dose inhalers, clinical comparisons suggest they provide similar control to dry powder inhalers.
Eszes, Noemi, Gabriele Nicolini, Chrystyn, Henry, Eszes Noemi, György Losonczy, Noemi Eszes, Henry Chrystyn, Müller, Veronika, Gabriella Gálffy, Chrystyn Henry, Nicolini Gabriele, Gálffy Gabriella, Andrea Bizzi, Lilla Tamási, Bizzi Andrea, Tamási Lilla, Gálffy, Gabriella, Tamási, Lilla, Müller Veronika, Losonczy, György, Nicolini, Gabriele, Bizzi, Andrea, Veronika Müller, Losonczy György   +23 more
core   +2 more sources

Safety and efficacy of fluticasone/formoterol combination therapy in adolescent and adult patients with mild-to-moderate asthma: a randomised controlled trial

BMC Pulmonary Medicine, 2012
Background This study investigated the efficacy and safety of a new asthma therapy combining fluticasone propionate and formoterol fumarate (fluticasone/formoterol; flutiform®), administered twice daily (b.i.d.) via a single aerosol inhaler, compared ...
Nathan Robert A, D’Urzo Anthony, Blazhko Viktor, Kaiser Kirsten   +3 more
doaj   +1 more source

Impact of Mechanistic Modeling and Simulation Methodologies on Product‐Specific Guidance Development for Non‐Orally Administered Drug Products

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 9, Page 1421-1430, September 2025.
ABSTRACT The U.S. Food and Drug Administration (FDA) publishes product‐specific guidances (PSGs), with bioequivalence (BE) recommendations for prospective generics. Developing BE recommendations for non‐orally administered drug products including long‐acting injectables (LAI), orally inhaled drug products, and drugs applied locally to the skin ...
Steven G. Chopski, Ross L. Walenga, Ming‐Liang Tan, Khondoker Alam, Andrew Babiskin, Lanyan Fang, Eleftheria Tsakalozou   +6 more
wiley   +1 more source

The double bronchodilation era: new capabilities in a new drug delivery device

Медицинский совет, 2022
A literature review presents the efficacy and safety of the new glycopyrronium bromide/formoterol fumarate (GP/FF) combination in the treatment of patients with chronic obstructive pulmonary disease according to the PINNACLE 1, 2, 3, 4 studies. There are
E. A. Orlova, I. P. Dorfman, M. A. Orlov, M. A. Abdullaev   +3 more
doaj   +1 more source

Characterisation of the novel quinoline RCD405: Relaxant effects on cholinergic and histaminergic tone in human bronchi and small airways

British Journal of Pharmacology, Volume 182, Issue 17, Page 4122-4133, September 2025.
Abstract Background and Purpose Increased contractility of human airway smooth muscle (hASM) is a hallmark of asthma and chronic obstructive pulmonary disease (COPD). Developing new classes of bronchodilators has proved to be challenging because of efficacy and safety concerns.
Paola Rogliani, Clive Page, Francesco Facciolo, Mia Lundblad, Luigino Calzetta   +4 more
wiley   +1 more source

Management of Primary Ciliary Dyskinesia in a Kartagener's Syndrome Patient With Total Situs Inversus

Respirology Case Reports, Volume 13, Issue 8, August 2025.
We report the case of a 62‐year‐old female patient with complete situs inversus of the chest and abdominal organs. Bronchoscopic washout of the lungs was performed for therapeutic benefit and culturing for targeted antibacterial therapy. This case highlights the importance of a comprehensive and effective management approach for patients with ...
Ivan H. Huang, Kenneth N. Dang, Saarang Kashyap, Alexander J. Sweidan   +3 more
wiley   +1 more source

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

Formoterol for the Treatment of Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2020
Donald P Tashkin Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USACorrespondence: Donald P TashkinDavid Geffen School of Medicine at UCLA, 10388 Le Conte Avenue, Los Angeles, CA 90095, USATel +1 310 825 3163Fax +1 310 ...
Tashkin DP
doaj  

Dose of Inhaled Corticosteroid in Chronic Obstructive Pulmonary Disease and Risks of Osteoporosis or Fracture—A Systematic Review and Meta‐Analysis

The Clinical Respiratory Journal, Volume 19, Issue 5, May 2025.
High‐dose, but not medium‐ and low‐dose, ICS use in COPD is associated with risks of osteoporosis or fractures. ABSTRACT Background Inhaled corticosteroid (ICS) is a major pharmacotherapy for chronic obstructive pulmonary disease (COPD), which is associated with various adverse effects.
Wang Chun Kwok, Chung Ki Tsui, Sze Him Isaac Leung, Shuk Man Ngai, David Chi Leung Lam, Mary Sau Man Ip, James Chung Man Ho   +6 more
wiley   +1 more source

Multicomponent Interventions for Adults With Cancer Cachexia: A Systematic Review

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Cancer cachexia has substantial impacts on people's quality of life. There is no current gold standard treatment, but the complex pathophysiology of cachexia suggests that a multitargeted and individualised treatment approach is needed.
Megan Bowers, Carmine Petrasso, Amy McLuskie, Joanne Bayly, Barry J. A. Laird, Irene J. Higginson, Matthew Maddocks   +6 more
wiley   +1 more source