Results 41 to 50 of about 1,168,780 (218)

Mid-Infrared Grating Couplers for Silicon-on-Sapphire Waveguides

IEEE Photonics Journal, 2012
Theoretical and experimental results of mid-infrared (mid-IR) gratings for coupling between transverse-electric (TE)/transverse-magnetic (TM) mode silicon-on-sapphire (SOS) waveguides and zirconium, barium, lanthanum, aluminum, and sodium fluoride (ZBLAN)
Zhenzhou Cheng, Xia Chen, C. Y. Wong, Ke Xu, Christy K. Y. Fung, Y. M. Chen, Hon Ki Tsang   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A Simple Transfer-Function-Based Approach for Estimating Material Parameters From Terahertz Time-Domain Data

IEEE Photonics Journal, 2014
A novel parametrically efficient approach to estimating the spectra of short transient signals is proposed and evaluated, with an application to estimating material properties, including complex refractive index and absorption coefficient, in the ...
K. M. Tych, C. D. Wood, W. Tych
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

TWDM-PON With Signal Remodulation and Rayleigh Noise Circumvention for NG-PON2

IEEE Photonics Journal, 2013
We propose and demonstrate a 40-Gb/s (4 × 10 Gb/s) downstream and 10-Gb/s (4 × 2.5 Gb/s) upstream time-wavelength-division-multiplexed passive optical network (TWDM-PON) using signal remodulation. Here, a downstream differential-phase-shift-
C. W. Chow, C. H. Yeh, K. Xu, J. Y. Sung, H. K. Tsang   +4 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

1-Tb/s WDM-OFDM-PON System With Subband Access Scheme and Flexible Subcarrier-Level Bandwidth Allocation

IEEE Photonics Journal, 2013
A novel subband access scheme for multiband high-speed orthogonal frequency division multiplexing (OFDM) passive optical network (PON) is proposed, where the granularity of the bandwidth allocation is as small as the bandwidth of just one subcarrier and ...
Cheng Lei, Minghua Chen, Hongwei Chen, Sigang Yang, Ying Yu, Shizhong Xie   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Analytical Expression of Average Power-Coupling Coefficients for Estimating Intercore Crosstalk in Multicore Fibers

IEEE Photonics Journal, 2012
In order to realize fast and accurate estimation of intercore crosstalk in bent multicore fibers (MCFs), an analytical expression of the average power-coupling coefficient (PCC) based on an exponential autocorrelation function is, for the first time ...
Masanori Koshiba, Kunimasa Saitoh, Katsuhiro Takenaga, Shoichiro Matsuo   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source