Results 51 to 60 of about 4,752,483 (291)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Evanescent-Light Deposition of Graphene Onto Tapered Fibers for Passive Q-Switch and Mode-Locker
IEEE Photonics Journal, 2012 We demonstrate the fabrication of graphene-deposited tapered fibers (GDTFs), which can be used as saturable absorbers (SAs) for pulsed lasers. The advantages of GDTF SAs include flexibility, all-fiber configuration, and high optical damage threshold. The
Jinzhang Wang +8 more
doaj +1 more source
Multiplicity Formula and Stable Trace Formula [PDF]
American Journal of Mathematics, 2019 Let $G$ be a connected reductive group over $\mathbb{Q}$. In this paper, we will stabilize the local trace formula, in particular, we construct the explicit form of the spectral side of stable local trace formula in the Archimedean case, when one component of the test function is cuspidal.
openaire +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
IEEE Photonics Journal, 2013 A 3-D numerical model has been developed to investigate the transient thermal, electrical, and optical output performance of a single-chip light-emitting diode (LED) with an interdigitated mesa geometry under dc operation and a multimicrochip LED under ...
Farn-Shiun Hwu +5 more
doaj +1 more source
, 2014 Let $E/F$ be an extension of number fields with $\mathrm{Gal}(E/F)$ simple and nonabelian. In [G] the first named author suggested an approach to nonsolvable base change and descent of automorphic representations of $\mathrm{GL}_2$ along such an ...
Getz, Jayce R., Herman, P. Edward
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IEEE Photonics Journal, 2012 In order to realize fast and accurate estimation of intercore crosstalk in bent multicore fibers (MCFs), an analytical expression of the average power-coupling coefficient (PCC) based on an exponential autocorrelation function is, for the first time ...
Masanori Koshiba +3 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Long-Period Fiber Grating Within D-Shaped Fiber Using Magnetic Fluid for Magnetic-Field Detection
IEEE Photonics Journal, 2012 A magnetic sensor utilizing long-period fiber grating (LPFG) written by high frequency CO2 laser pulses in a D-shaped fiber and the magneto-optical effect of magnetic fluid is proposed.
Lei Gao +6 more
doaj +1 more source