Results 11 to 20 of about 1,464,537 (295)

A continuous/discontinuous Galerkin formulation for a strain gradient-dependent damage model [PDF]

open access: yes, 2004
The numerical solution of strain gradient-dependent continuum problems has been hindered by continuity demands on the basis functions. The presence of terms in constitutive models that involve gradients of the strain field means that the $C^0$ continuity
G. N. Wells   +2 more
core   +18 more sources

Accounting for psychological problems: How user-friendly is formulation? [PDF]

open access: yes, 2009
Formulation, with its use of psychosocial explanations for psychological problems, has the potential to normalise and destigmatise clients’ difficulties. However, we present findings from a recent study which suggest that for mental health service users,
Leeming, Dawn   +2 more
core   +4 more sources

Non-degenerate umbilics, the path formulation and gradient bifurcation problems [PDF]

open access: yes, 2004
Parametrised contact-equivalence is successful for the understanding and classification of the qualitative local behaviour of bifurcation diagrams and their perturbations. Path formulation is an alternative point of view.
Sitta, AM, Furter, JE
core   +6 more sources

Enhancing Dissolution and Oral Bioavailability of Ursodeoxycholic Acid with a Spray-Dried pH-Modified Extended Release Formulation

open access: yes, 2022
Ursodeoxycholate (UDCA) has low oral bioavailability and pH-dependent solubility and permeability. Thus, we developed a pH-modified extended-release formulation of UDCA using Na(2)CO(3) as the alkalizing agent and hydroxypropyl methylcellulose (HPMC) as ...
Lee, Jaehyeok   +11 more
core   +1 more source

DoE-Assisted Development of a Novel Glycosaminoglycan-Based Injectable Formulation for Viscosupplementation

open access: yes, 2020
The aim of the present work was the development of a novel glycosaminoglycan (GAG)-based injectable formulation intended for intra-articular administration that should best mimic the healthy synovial fluid.
Marta Cicognani   +4 more
core   +1 more source

Palatability and Stability Studies to Optimize a Carvedilol Oral Liquid Formulation for Pediatric Use

open access: yes, 2023
Carvedilol (CARV) is a blocker of α- and β- adrenergic receptors, used as an “off-label” treatment for cardiovascular diseases in pediatrics.
Encarnacion Garcia-Montoya   +7 more
core   +1 more source

Counseling case formulation as metaphor [PDF]

open access: yes, 2018
Case formulation is the rhetorical centerpiece of counseling. Case formulation arises from empirical assessment and directs evidence-based intervention. Case formulation emanates from an epistemology that is enlivened in an arcane rhetoric.
Creed, Alison, McIlveen, Peter
core   +1 more source

Rapid and selective characterization of antibody-drug conjugates in complex sample matrices by native affinity liquid chromatography-mass spectrometry

open access: yesmAbs
Antibody-drug conjugates (ADCs) and other biopharmaceuticals require robust analytical methods to assess biotransformation in biological matrices. Current approaches often require off-line enrichment and extensive chromatographic separation, limiting ...
Dan Bach Kristensen   +12 more
doaj   +1 more source

Working paper: Preliminary formulation of alternate plans for the Lake Pontchartrain, Louisiana and Vicinity Hurricane Protection Project

open access: yes, 2022
WORKING PAPERS PRELIMINARY FORMULATION OF ALTERNATIVE PLANS F.OR THE LAKE PONTCHARTRAIN, LOUISIANA AND VICINITY HURRICANE PROTECTION PROJECT DRAFT ~ Prepared by: Plan Formulation Branch Planning Division USAED, New Orleans Date Prepared: :, June 1980 .. .
Plan Formulation Branch; Planning Division; USAED New Orleans
core  

Risk control of host cell proteins in one therapeutic antibody produced by concentrated fed‐batch (CFB) mode

open access: yesEngineering in Life Sciences, 2023
Multiple control strategies, including a downstream purification process with well‐controlled parameters and a comprehensive release or characterization for intermediates or drug substances, were implemented to mitigate the potential risk of host cell ...
Yiling Lu   +9 more
doaj   +1 more source

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