Results 11 to 20 of about 1,516,376 (247)
A continuous/discontinuous Galerkin formulation for a strain gradient-dependent damage model [PDF]
, 2004 The numerical solution of strain gradient-dependent continuum problems has been hindered by continuity demands on the basis functions. The presence of terms in constitutive models that involve gradients of the strain field means that the $C^0$ continuity
G. N. Wells +2 more
core +13 more sources
Case Study on Formulating a Multidose Lyophilized Measles-Rubella (MR) Vaccine Candidate for Local Manufacturing in Africa: Lab-Scale Results and Lessons Learned for Future Technology Transfer [PDF]
VaccinesBackground/Objectives: Local manufacturing of Measles-Rubella (MR) vaccines is part of a multifaceted approach to improve vaccine accessibility in Africa, yet process development and technology transfer challenges remain for large-scale production of ...
Kathryn Secrist +9 more
doaj +2 more sources
Accounting for psychological problems: How user-friendly is formulation? [PDF]
, 2009 Formulation, with its use of psychosocial explanations for psychological problems, has the potential to normalise and destigmatise clients’ difficulties. However, we present findings from a recent study which suggest that for mental health service users,
Leeming, Dawn +2 more
core +4 more sources
mAbs, 2022 Monoclonal antibody (mAb) aggregation can present major challenges for the development of biotherapeutics. An understanding of the molecular mechanisms of mAb aggregation is highly desirable both because it allows the performance of informed risk ...
Michael J. Knight +4 more
doaj +1 more source
Bulletin of the National Research Centre, 2021 Background Indonesia has started the big project of COVID-19 vaccination program since 13 January 2021 by employing the first shot of vaccine to the President of Indonesia as the outbreak and rapid transmission of COVID-19 have endangered not only ...
Reviany V. Nidom +10 more
doaj +1 more source
Pediatric Mini-Tablets: Predicting the Hidden Risk of Fill Errors
Pharmaceutics, 2023 Compressed mini-tablets in sachets or capsules are an increasingly prevalent oral solid dosage form for pediatric products. While resembling adult tablets, additional care is required to control weight and potency (blend uniformity) variation due to ...
Brandon G. Gerberich +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Measles (Me) and rubella (Ru) viral diseases are targeted for elimination by ensuring a high level of vaccination coverage worldwide. Less costly, more convenient MeRu vaccine delivery systems should improve global vaccine coverage, especially in low ...
Ying Wan +7 more
doaj +1 more source
Aquaculture Nutrition, 2022 Increasing dietary replacement levels of fish meal by alternative plant proteins are of value for aquaculture. Here, a 10-week feeding experiment was undertaken to explore the effects of fish meal replacement by mixed plant protein (at a 2 : 3 ratio of ...
Ya-Kang Han +5 more
doaj +1 more source
Prediction of long-term polysorbate degradation according to short-term degradation kinetics
mAbs, 2023 Polysorbates (PSs) are a class of surfactants commonly used in the formulation of protein therapeutic agents to provide protection against denaturation and aggregation. When the PS in these drug formulations degrades, loss of stabilization of the protein
Sisi Zhang +8 more
doaj +1 more source
Formulation and preclinical studies with a trivalent rotavirus P2-VP8 subunit vaccine
Human Vaccines & Immunotherapeutics, 2020 More effective rotavirus vaccines are essential for preventing extensive diarrheal morbidity and mortality in children under five years of age in low-resource regions.
Kyle Lakatos +3 more
doaj +1 more source