Results 21 to 30 of about 4,726,473 (338)

On the equivalence of strong formulations for capacitated multi-level lot sizing problems with setup times [PDF]

, 2012
Several mixed integer programming formulations have been proposed for modeling capacitated multi-level lot sizing problems with setup times. These formulations include the so-called facility location formulation, the shortest route formulation, and the ...
A. Migdalas, C. Mercé, F. Sahling, G. Belvaux, G.D. Eppen, G.L. Nemhauser, H. Stadtler, H. Tempelmeier, H. Tempelmeier, I. Barany, Joseph Geunes, K. Akartunalı, Kerem Akartunalı, Leyuan Shi, M. Denizel, N. Absi, P. Billington, T. Wu, Tao Wu   +18 more
core   +1 more source

Risk control of host cell proteins in one therapeutic antibody produced by concentrated fed‐batch (CFB) mode

Engineering in Life Sciences, 2023
Multiple control strategies, including a downstream purification process with well‐controlled parameters and a comprehensive release or characterization for intermediates or drug substances, were implemented to mitigate the potential risk of host cell ...
Yiling Lu, Jun Lin, Tianze Bian, Jin Chen, Dan Liu, Mingjun Ma, Zhen Gao, Jiemin Chen, Dianwen Ju, Xing Wang   +9 more
doaj   +1 more source

Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation

BMC Immunology, 2018
Background The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development.
Sumera Y. Younis, Christophe Barnier-Quer, Simon Heuking, Vinod Sommandas, Livia Brunner, Nicole vd.Werff, Patrice Dubois, Martin Friede, Clemens Kocken, Nicolas Collin, Ed Remarque   +10 more
doaj   +1 more source

To formulate or not to formulate? A case study [PDF]

British Journal of Mental Health Nursing, 2016
Personality disorders are common in specialist forensic mental health services and can complicate the treatment and care of people who may also have other co-morbid mental health problems—especially because they are based on unclear and unvalidated descriptions.
Houghton, Karrie, Jones, Emma
openaire   +1 more source

Strategy Formulation—Introduction to a Grouping on Strategy Formulation [PDF]

Management Science, 1978
Introduction to a special section devoted to strategy formulation.
Henry Mintzberg, Melvin F. Shakun
openaire   +1 more source

LC_2 formulation of supergravity

, 2009
We formulate (N=1, d=11) supergravity in components in light-cone gauge (LC_2) to order $\kappa$. In this formulation, we use judicious gauge choices and the associated constraint relations to express the metric, three-form and gravitino entirely in ...
C Aragone, E Cremmer, F Brandt, G Leibbrandt, L Brink, LPS Singh, M Goroff, M Kaku, P Nieuwenhuizen Van, RJ Hughes, RR Metsaev, S Ananth, S Ananth, S Deser, S Mandelstam, Sudarshan Ananth, TL Curtright   +16 more
core   +1 more source

Problem Formulation and Fairness [PDF]

FAT, 2019
Formulating data science problems is an uncertain and difficult process. It requires various forms of discretionary work to translate high-level objectives or strategic goals into tractable problems, necessitating, among other things, the identification ...
Samir Passi, Solon Barocas
semanticscholar   +1 more source

Rapid and selective characterization of antibody-drug conjugates in complex sample matrices by native affinity liquid chromatography-mass spectrometry

mAbs
Antibody-drug conjugates (ADCs) and other biopharmaceuticals require robust analytical methods to assess biotransformation in biological matrices. Current approaches often require off-line enrichment and extensive chromatographic separation, limiting ...
Dan Bach Kristensen, Nanna Sofie Eskesen, Clara Coll-Satue, Alexandre Nicolas, Jan Kirkeby Simonsen, Lykke Rasmussen, Trine Meiborg Sloth, Martin Ørgaard, Elizabeta Madzharova, Simon Krabbe, Katrine Zinck Leth, Pernille Foged Jensen, Alain Beck   +12 more
doaj   +1 more source

Postmodern String Theory: Stochastic Formulation

, 1994
In this paper we study the dynamics of a statistical ensemble of strings, building on a recently proposed gauge theory of the string geodesic field. We show that this stochastic approach is equivalent to the Carath\'eodory formulation of the Nambu-Goto ...
A. Aurilia, A. Aurilia, A. Aurilia, A. Aurilia, A. Linde, A. Schild, C. Marshall, E. Santamato, E. Santamato, E. Spallucci, E.J. Copeland, E.J. Heller, E.S. Fradkin, F. Embacher, H.A. Kastrup, H.A. Kastrup, H.B. Nielsen, I. Vanzetta, J. Stachel, M. Kalb, T. Eguchi, Y. Hosotani, Y. Nambu, Y. Nambu, Y. Nambu, Y. Nambu, Y. Nambu   +26 more
core   +1 more source

Thin films as an emerging platform for drug delivery

Asian Journal of Pharmaceutical Sciences, 2016
Pharmaceutical scientists throughout the world are trying to explore thin films as a novel drug delivery tool. Thin films have been identified as an alternative approach to conventional dosage forms.
Sandeep Karki, Hyeongmin Kim, Seon-Jeong Na, Dohyun Shin, Kanghee Jo, Jaehwi Lee   +5 more
doaj   +1 more source