Results 31 to 40 of about 1,177,031 (317)

Retraction Note: Effects of DA-5513 on alcohol metabolism and alcoholic fatty liver in rats

Laboratory Animal Research, 2020
An amendment to this paper has been published and can be accessed via the original article.
Jae Young Yu, Hanh Thuy Nguyen, Chul Soon Yong, Hyoung Geun Park, Joon Ho Jun, Jong Oh. Kim   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Artificial intelligence accelerates drug discovery and enhances commercialization efficiency

Discover Artificial Intelligence
Artificial Intelligence has enriched drug Discovery and development, making it faster and easier. This Review article summarizes the use of AI across various stages of drug discovery and development, as well as in marketing and commercialization. It also
Vrushab Sunil Pipada, Dileep J. Babu Bikkina, Suresh Kumar Joshi, Narendra Reddy Tharigoppala, Subhash Zade, Rajesh Vooturi   +5 more
doaj   +1 more source

Prediction of long-term stability of high-concentration formulations to support rapid development of antibodies against SARS-CoV-2

mAbs
Long-term stability of antibody therapeutics is required to ensure their safety and efficacy when administered to patients. However, obtaining shelf life supporting, long-term stability data are often a limiting factor for new drug candidates starting ...
Lin Luo, Michael Meleties, Julie Beaudet, Yuan Cao, Wenhua Wang, Qingyan Hu, Sarah Sidnam, Michele Lastro, Dingjiang Liu, Mohammed Shameem   +9 more
doaj   +1 more source

Repellent efficacy of Crotalaria burhia and Anacardium occidentale against Odontotermes obesus (Isoptera: Termitidae) under laboratory conditions

The Indian Journal of Agricultural Sciences, 2015
Laboratory studies were carried out at bioassay lab, Institute of Pesticide Formulation Technology, Gurgaon to incur the repellent efficacy of Crotalaria burhia Buch.-Ham and Anacardium occidentale L. against Odontotermes obesus (Rambur).
RANJITH M, D R BAJYA, T MANOHARAN, S SRIDHARAN, S KUTTALAM   +4 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

An analytical formulation of CPMAS [PDF]

Solid State Nuclear Magnetic Resonance, 2003
An exact expression for the cross polarization between two spin-1/2 particles is derived from the quantum Liouville equation. This is given in the form of two integrodifferential equations. These can be solved exactly in the static case (no sample spinning) and a powder average performed numerically.
Marica, F., Snider, R. F.
openaire   +3 more sources

Injection site reactions of biologics and mitigation strategies

AAPS Open
Biological products administered via subcutaneous (SC) injections offer an effective and convenient alternative to those administered via traditional intravenous injections and have gained a significant increase among approved drugs in recent years ...
Li Zhi, Dingjiang Liu, Mohammed Shameem
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Formulation and evaluation of ivermectin emulgel formulations

World Journal of Current Medical and Pharmaceutical Research, 2023
Ivermectin, a broad-spectrum antiparasitic agent, has demonstrated significant therapeutic efficacy against various skin conditions. However, it's poor skin permeability and limited stability often hinder its clinical application. Emulgel, a hybrid dosage form combining the advantages of both emulsions and gels, has emerged as a promising topical ...
Vaibhav Joshi, Kapil Kumar, Anjali Negi, Aparna Joshi, Vaishali Rajput   +4 more
openaire   +1 more source