Results 81 to 90 of about 3,527,229 (316)
An Imine-Based Two-Dimensional Covalent Organic Framework for Gemcitabine Delivery
Colloids and InterfacesA 2D imine-linked covalent organic framework (COF) with good biocompatibility was synthesized using o-Dianisidine and 1,3,5-Triformylbenzene. The synthesized COF was characterized by using the Fourier transform infrared (FTIR), thermogravimetry analysis (
Kajal Kaliya +3 more
doaj +1 more source
The Indian Journal of Agricultural Sciences, 2015 Field studies were undertaken at research farm, IPFT, Gurgaon to evaluate the efficacy of indoxacarb 5% + fipronil 5% SC at four doses, viz. 100 (50+50) g a.i./ha ,125 (62.5+62.5) g a.i./ha, 150 (75+75) g a.i./ha and 250 (125+125) g a.i./ha, along with ...
D R BAJYA, M RANJITH, M C LAKHARAN
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
CellsTau protein, a neuron-enriched microtubule-associated protein encoded by the MAPT gene, plays pivotal roles in microtubule stabilisation, axonal transport, and synaptic plasticity.
Xinai Shen +4 more
doaj +1 more source
Formulation design and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique [PDF]
, 2004 Mukesh Gohel +5 more
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Indian Journal of Agricultural Sciences, 2016 Field trials were carried out at the Institute of Pesticide Formulation Technology, Gurgaon, Haryana, India during kharif 2013 and 2014 to evaluate the field efficacy and to fix the correct dose of novel molecule cyenopyrafen 30% SC for the management ...
D R BAJYA, M RANJITH
doaj +1 more source