Results 61 to 70 of about 1,516,376 (247)

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

RNA-lipid nanoparticle therapeutics for women’s health

Frontiers in Nanotechnology
Ribonucleic acid-lipid nanoparticle (RNA-LNP) therapeutics, a powerful nanomedicine platform, have already demonstrated their efficacy in diverse applications.
Alireza Nomani, Aishwarya Saraswat, Yu Zhang, Ashwin C. Parenky, Chun-Tien Jimmy Kuo, Heather Brown, Suzanne Hartford, Bindhu Rayaprolu, Amardeep Singh Bhupender Bhalla, Mohammed Shameem   +9 more
doaj   +1 more source

Recent Advances in Amorphous Solid Dispersions: Preformulation, Formulation Strategies, Technological Advancements and Characterization

, 2022
Amorphous solid dispersions (ASDs) are among the most popular and widely studied solubility enhancement techniques. Since their inception in the early 1960s, the formulation development of ASDs has undergone tremendous progress.
Pavan Kumar Nukala, Juluri, Abhishek, Srushti Tambe, Girish Nihalani, Rongala, Gopinath, Meruva, Sai Kishore, Sai Kishore Meruva, Nihalani, Girish, Pradeep Kumar Bolla, Gopinath Rongala, Jain, Divya, Abhishek Juluri, Nukala, Pavan Kumar, Tambe, Srushti, Bolla, Pradeep Kumar, Hemanth Kumar Mamidi, Mamidi, Hemanth Kumar, Divya Jain   +17 more
core   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Quality Assessment of Ojeok-San, a Traditional Herbal Formula, Using High-Performance Liquid Chromatography Combined with Chemometric Analysis

Journal of Analytical Methods in Chemistry, 2015
Ojeok-san (OJS) is a traditional herbal formula consisting of 17 herbal medicines that has been used to treat various disorders. In this study, quantitative analytical methods were developed using high-performance liquid chromatography equipped with a ...
Jung-Hoon Kim, Chang-Seob Seo, Seong-Sil Kim, Hyeun-Kyoo Shin   +3 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

A Design of Experiments Approach for Enhancing Room Temperature Stability of a Lyophilised and Paper-Based Bacterial Cell-Free System

Bioengineering
Centralised cell-based biomanufacturing severely limits applicability in low-resource and extreme environments, where a largely untreated human population is present.
Tejasvi Shivakumar, Joshua Clark, Alice Goode, Valentine E. Anyanwu, Philip M. Williams   +4 more
doaj   +1 more source

Non-degenerate umbilics, the path formulation and gradient bifurcation problems [PDF]

, 2004
Parametrised contact-equivalence is successful for the understanding and classification of the qualitative local behaviour of bifurcation diagrams and their perturbations. Path formulation is an alternative point of view.
Sitta, AM, Furter, JE
core   +3 more sources

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Unlocking norepinephrine potential innovations in formulation and smart systems

Discover Pharmaceutical Sciences
Norepinephrine (NE), a critical neurotransmitter and hormone, profoundly influences cardiovascular function and stress response. However, inherent pharmacokinetic challenges, notably rapid enzymatic degradation and a short half-life, mandate continuous ...
Samarth Kumar, Sachin N. Sanap, Milan Vasoya, Prachi Pandey, Ajay Khopade, Krutika K. Sawant   +5 more
doaj   +1 more source