Results 211 to 220 of about 316,859 (287)

Chemical Synthesis and Functional Screening of an 800 000‐Member Library Using a Peptide‐Pairing Strategy

Angewandte Chemie, EarlyView.
Chemical peptide synthesis allows the generation of structurally highly diverse compounds suited for ligand development, but current methods in parallel peptide synthesis limit the achievable library size to a few thousand. A strategy is presented based on combinatorial pairing of short peptides via disulfide linkage that enables the generation and ...
Anne Zarda, Xingwang Deng, Edward Will, Thomas Emel, Maylin Romero, Christian Heinis   +5 more
wiley   +1 more source

Intervertebral disc degeneration affects the flexibility but not the vulnerability of the cervical spine - An in vitro study

Brain and Spine
C. Liebsch, A.K. Greiner-Perth, M. Vogt, V. Vieres, R. Jonas, H.J. Wilke   +5 more
doaj   +1 more source

Effects of Physical Activity on Brain White Matter Integrity Are Region-, Dose-, and Age-Dependent: Findings From the Population-Based Rhineland Study. [PDF]

Aging Cell
Saxler E, Fox FAU, Koch A, Yang X, Zeng W, Estrada S, Breteler MMB, Aziz NA.   +7 more
europepmc   +1 more source

Mechanistische Diversität in der photoangeregten Radikal‐Redoxchemie: Eine kritische Evaluierung

Angewandte Chemie, EarlyView.
Für viele prominente Beispiele der Photoredox‐Katalyse wird angenommen, dass sie über die Anregung einer offenschaligen („open‐shell“) Zwischenform des Katalysators ablaufen. Es wird jedoch intensiv darüber diskutiert, ob solche Mechanismen realistisch sind und, falls ja, wie genau sie ablaufen können.
Samuel J. Horsewill, Ryan Phelps, Joshua P. Barham, Daniel J. Scott   +3 more
wiley   +1 more source

Berichte aus der Werkstatt für Griff-Forschung

, 1937
Werkstätte für Griff-Forschung (Karlsruhe)
core  

The genotypic and phenotypic landscape of PDHA1-related pyruvate dehydrogenase complex deficiency. [PDF]

Brain
Merkevicius K, Smirnov D, Schlieben LD, Ganetzky R, Feichtinger RG, Jiang H, Fang F, Ebihara T, Murayama K, Ferrera G, Ardissone A, Rokicki D, Wesol-Kucharska D, Schröder S, Bauer P, Bertoli-Avella A, Østergaard E, Freisinger P, Janssen MCH, Wagner M, Abouyousef O, Alhaddad B, AlAbdi L, Alkuraya F, Alston CL, Baghdasaryan A, Barca D, Barić I, Bellusci M, Bevot A, Boltshauser E, Borggraefe I, Bouchereau J, Bruno C, Burnyte B, Calhoun A, Casas K, Coker M, Crushell E, De Lonlay P, Dionisi-Vici C, Distelmaier F, Falk MJ, Ferreira AC, Ferreira CR, Ficicioglu C, Gokçay GF, Häberle J, Heath O, Hellenschmidt A, Hoefele J, Hoffmann GF, Honzik T, Huemer M, Janeiro P, Karaa A, Kasapkara ÇS, Kern I, Klepper J, Klopstock T, Knerr I, Koch J, Krumina Z, Lamperti C, Lebigot E, Liu Z, Maier EM, Martinelli D, McFarland R, Mendelsohn B, Molnar MJ, Mundy H, Nassogne MC, Oliveira A, Õunap K, Panicucci C, Parikh S, Peters H, Pichard S, Plecko B, Ramadža DP, Repetto GM, Rivera I, Rodenburg RJ, Rossi A, Schiff M, Seidemann K, Smith WE, Soares S, Siri B, Steinbrucker K, Striano P, Sykut-Cegielska J, Tal G, Taylor RW, Tsiakas K, Kalkan Ucar S, Hoytema van Konijnenburg E, Woidy M, Yaplito-Lee J, Yildiz Y, Zenker M, Zsidegh P, Westphal D, Sperl W, Meitinger T, Brown GK, Prokisch H, Mayr JA, Wortmann SB.   +109 more
europepmc   +1 more source

Engineering Ferrimagnetic Interactions in Molecular Quantum Systems

Angewandte Chemie, EarlyView.
Heterospin nanographene architectures—constructed by covalently linking spin‐1/2$\nicefrac {1}{2}$ and spin‐1 triangular units via on‐surface synthesis—are characterized by bond‐resolved scanning probe microscopy. Inelastic electron tunneling spectroscopy probes exchange interactions within a Heisenberg model, revealing both compensated (S=0$S=0$) and ...
Elia Turco, Fupeng Wu, Annika Bernhardt, Nils Krane, Ji Ma, Roman Fasel, Michal Juríček, Xinliang Feng, Pascal Ruffieux   +8 more
wiley   +1 more source

Machine learning for population-level risk prediction of future cholangiocarcinoma. [PDF]

EBioMedicine
van Haag F, Clusmann J, Koop PH, Goodson R, Tryakin I, Wakabayashi SI, Seibel T, Jakhar N, Huang HYR, Zhang DY, Zandvakili I, Kimura T, Tamaki N, Krishnan A, Rodrigues PM, Banales JM, Gerussi A, Saborowski A, Rader D, Kather JN, Schneider KM, Schneider CV.   +21 more
europepmc   +1 more source

Light‐Driven Out‐of‐Equilibrium Helicity Control in a Diarylethene–Helicene Photosystem

Angewandte Chemie, EarlyView.
Distinct energy landscapes of different helicities in the open and closed states of a diarylethene–helicene photoswitch enable a light‐driven energy ratchet. Helix inversion occurs selectively in the closed form, and the resulting helicity is transferred and kinetically trapped upon ring opening, generating a persistent out‐of‐equilibrium chiral state ...
Eric Sidler, Jinghao Wang, Christina Vallina, Ben L. Feringa   +3 more
wiley   +1 more source

The influence of low-magnitude high-frequency vibration on pressure in the nucleus changes with degeneration – intradiscal pressure measurements in a degenerative disc organ culture model

Brain and Spine
M. Vogt, F. Figel, G. Teixeira, J.U. Jansen, C. Neidlinger-Wilke, H.J. Wilke   +5 more
doaj   +1 more source