Results 61 to 70 of about 1,336,459 (329)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Applied SciencesMine water inrush remains one of the major hazards threatening the safety of coal mining operations. To assess the feasibility of integrating transient electromagnetic (TEM) and direct-current (DC) methods for advanced detection in underground settings ...
Yunlan He +5 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Meitian dizhi yu kantanObjective and MethodDensely distributed sub-seismic faults have emerged as a major hidden disaster-causing geological factor, heavily influencing both the production efficiency and operational safety of coal mines. To achieve precise advance detection of
Haodang LI +5 more
doaj +1 more source
Forward Modeling of Double Neutron Stars: Insights from Highly-Offset Short Gamma-Ray Bursts
, 2020 We present a detailed analysis of two well-localized, highly offset short gamma-ray bursts---GRB~070809 and GRB~090515---investigating the kinematic evolution of their progenitors from compact object formation until merger. Calibrating to observations of
Berry, Christopher P. L. +5 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Applied SciencesThe electromagnetic method is widely used in mineral exploration, geothermal resource exploration, and deep earth structure detection. To improve the resolution and positioning accuracy of magnetotelluric surveys for targets beneath cover, it is ...
Hui Zhang, Fajian Nie
doaj +1 more source
Applied Sciences, 2020 The role of rectus femoris (RF) muscle during walking was analyzed through musculoskeletal models to understand the effects of muscle weakness and hyperactivity.
Carlo Albino Frigo +2 more
doaj +1 more source
Fast Point Spread Function Modeling with Deep Learning
, 2018 Modeling the Point Spread Function (PSF) of wide-field surveys is vital for many astrophysical applications and cosmological probes including weak gravitational lensing. The PSF smears the image of any recorded object and therefore needs to be taken into
Amara, Adam +4 more
core +1 more source
Moving Forward: On the Limits of Motor-Based Forward Models
Trends in Cognitive Sciences, 2019 The human ability to anticipate the consequences that result from action is an essential building block for cognitive, emotional, and social functioning. A dominant view is that this faculty is based on motor predictions, in which a forward model uses a copy of the motor command to predict imminent sensory action-consequences. Although this account was
Dogge, Myrthel +2 more
openaire +4 more sources