Results 71 to 80 of about 15,465 (169)
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada +13 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina +2 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Packaging Technology and Science, EarlyView.Biodegradable cassava starch films were developed incorporating micro‐ and nanoencapsulated pomegranate seed oil (PSO). The films exhibited enhanced mechanical flexibility, antioxidant activity and UV‐barrier properties. Particle size influenced the functional behaviour, highlighting lipid encapsulation as a key strategy to stabilize bioactive ...
Amanda Tibães Lopes +7 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT As a promising alternative to sluggish Li2CO3‐based Li‐CO2 electrochemistry, Li2C2O4 offers a favorable 2e− discharge pathway, yet its selective formation and reversible decomposition remain debated. Herein, we propose a nonmetal‐metal synergistic catalyst—B‐Ti coregulated layered transition metal boride Ti18B18O9/graphene (B‐Ti/TiBOG)—to ...
Qiong Peng +8 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT The past decade has witnessed a burgeoning demand of metals for global industrial development and infrastructure. Meanwhile, the depletion of mineral resources and the environmental damage caused by wastewater discharges pose significant threats to both economic and ecological sustainability. Fortunately, metal‐containing wastewaters also hold
Fei Zhang +6 more
wiley +1 more source
8-Methoxypeucedanin: Evaluation of Anxiolytic Effects and Modulation of Neuronal Activity Related Genes in a Zebrafish Anxiety Mode. [PDF]
Int J Mol SciWidelski J +7 more
europepmc +1 more source
Rare Metals, EarlyView.ABSTRACT Against the backdrop of global clean energy transition and surging demand for lithium resources, lithium extraction from salt lakes presents unprecedented development opportunities. Nanofiltration (NF) membrane technology, recognized for its efficiency, energy savings, and environmental benefits, demonstrates significant application potential ...
Wen‐Feng Li +5 more
wiley +1 more source
An advanced network pharmacology investigation of Shufeng Jiedu formula in the treatment for respiratory tract infection based on LC-MS, data mining, molecular docking, and molecular dynamic simulation. [PDF]
Brief BioinformZhang Y +8 more
europepmc +1 more source
Small, EarlyView.Little is known about the effects of polystyrene nanoplastics (PS‐NPs) on gonadotropin releasing hormone (GnRH) neurons, which control puberty onset and fertility. By applying tailored in vitro GnRH neuron models, this article shows how PS‐NPs are internalized and impact hormone secretion and cell migration, through gene expression changes. Ultimately,
Federica Amoruso +14 more
wiley +1 more source