Results 141 to 149 of about 3,808 (149)

Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration

Aging Cell, EarlyView.
Overview of Dysregulated Cell Cycle Mechanisms in Neuronal Cells. A nuclear import block drives cell cycle re‐entry from G0, culminating in cell cycle arrest at G1/S. This cell cycle arrest is associated with activation of CKIs from the INK locus (p15, p16, p18, p19) and Cip/Kip (p21, p27) which act on specific CDK/Cyclin complexes.
Jonathan Plessis‐Belair, Taylor Russo, Markus Riessland, Roger B. Sher   +3 more
wiley   +1 more source

Blockade of insulin receptor signaling in the medullary cardiovascular centers impairs open-loop arterial baroreflex function via attenuated neural arc in healthy male rats. [PDF]

FASEB J
Hori A, Kawada T, Hotta N, Fukazawa A, Estrada JA, Kim HK, Iwamoto GA, Smith SA, Vongpatanasin W, Mizuno M.   +9 more
europepmc   +1 more source

Activation of the nucleus accumbens promotes place preference and counteracts stress-induced hyperthermia. [PDF]

iScience
Setoyama H, Ota S, Yoshida M, Kawashima S, Kusumoto-Yoshida I, Kashiwadani H, Kuwaki T.   +6 more
europepmc   +1 more source

Plasticity of visual looming response reveals a dissociation of innate and learned components

Conway PB, Autore L, Muñoz Zamora A, Harel A, Tavallaei AA, Winston SM, Ortega-de San Luis C, O’Leary JD, Brimble MA, Vetere G, Ryan TJ.   +10 more
europepmc   +1 more source

Predicting viral host codon fitness and path shifting through tree-based learning on codon usage biases and genomic characteristics. [PDF]

Sci Rep
Su S, Ni Z, Lan T, Ping P, Tang J, Yu Z, Hutvagner G, Li J.   +7 more
europepmc   +1 more source

Network pharmacology and experimental validation to investigate the mechanism of action of Zhilong Huoxue Tongyu capsule in the prevention and treatment of diabetic cardiomyopathy. [PDF]

PLoS One
Yang F, Luo G, Liu MN, Liu P, Wu D, Chen HL, Li S, Yang SJ, Dong L.   +8 more
europepmc   +1 more source

Polymorphic potential of SRF binding site of c-Fos gene promoter: in vitro study. [PDF]

RSC Adv
Profantová B, Římal V, Profant V, Socha O, Barvík I, Štěpánková H, Štěpánek J.   +6 more
europepmc   +1 more source

A navigational risk evaluation of ferry transport: Continuous risk management matrix based on fuzzy Best-Worst Method. [PDF]

PLoS One
Pham LT, Hoang LV.
europepmc   +1 more source

Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2

Mitic I, Michie KA, Jacques DA.
europepmc   +1 more source