Results 111 to 120 of about 1,416 (173)

Molecular Basis of Surfactin-Induced Macrophage Modulation and Its Implications in Medication-Related Osteonecrosis of the Jaw Pathogenesis. [PDF]

Int J Mol Sci
Kodama-Maruyama Y, Tsurushima H, Koga A, Nagai-Yoshioka Y, Yamasaki R, Habu M, Yoshioka I, Ariyoshi W.   +7 more
europepmc   +1 more source

Silk Fibroin‐Modified Titanium Implants for Bone Tissue Engineering: Structural Basis, Functionalization and Composite Strategies

Macromolecular Bioscience, Volume 26, Issue 8, August 2026.
Silk fibroin coatings transform inert 3D‐printed porous titanium scaffolds into intelligent, bioactive implants. Leveraging its pH‐responsive structure and tunable degradation, silk fibroin enables spatiotemporal drug delivery, promotes osteoblast activity, and modulates macrophage immunity.
Jiajun Liu, Yan Wang, Xin Li, Guang Li, Zexin Zheng, Lu Zhang, Xiaotian Feng, Tiancheng Ma, Yujing Chen, Yanxin Li, Yibo Liu, Benchao Dong, Peichuan Yang, Yan Li, Mengran Qin, Jianxiong Ma   +15 more
wiley   +1 more source

Repeated Stress Escalates Aggression and Activity in Fronto-Limbic Regions in Cntnap2^-/^- Mice. [PDF]

Genes Brain Behav
Hertweck CH, Carter CA, McDaniel SS, Llorach P, Tilton HE, Kodali A, Christoffel DJ, Walsh JJ.   +7 more
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

A scheduling perspective on modular educational systems in Europe. [PDF]

Heliyon
Ruiz-Torrubiano R, Knopp S, Krystallidis A, Wolf LM.   +3 more
europepmc   +1 more source

High‐throughput mutational analysis of F1‐ATPase by integrated cell‐free protein synthesis and single‐molecule rotation assay

Protein Science, Volume 35, Issue 8, August 2026.
Abstract F1‐ATPase (F1) is a rotary molecular motor that hydrolyzes adenosine triphosphate (ATP) to drive rotation of the central subunit against the surrounding stator ring. Single‐molecule rotation assays of mutated F1s have elucidated the roles of residues and regions in the chemo‐mechanical coupling mechanism, yet comprehensive mutational ...
Mai Taguchi, Tatsuya Oya, Hiroshi Ueno, Hiroyuki Noji   +3 more
wiley   +1 more source

Using Stochastic Simulation‐Estimation and Automated Model Development to Assess Power and Accuracy for Covariate Identification

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT When study designs are evaluated using clinical trial simulations for their ability to identify covariate effects in population pharmacokinetic (PopPK) modeling, it is typically assumed that the true model will be known at the data analysis stage. In this study, this was compared with the more realistic assumption that the PopPK model needs to
Ya‐Han Hsu, Bárbara Costa, Nuno Vale, Thomas P. C. Dorlo, Mats O. Karlsson   +4 more
wiley   +1 more source

Electroconvulsive therapy improves distal colonic motility via the subdiaphragmatic vagus nerve in depressive-like mice. [PDF]

Sci Rep
Dai M, Li Y, Tian Y.
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source