Results 81 to 90 of about 1,416 (173)

Molecular Mechanisms of Age‐Related Taste Dysfunction Deciphered by Spatiotemporal Transcriptomics

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Multi‐omics profiling reveals that aging impairs stem/progenitor cell differentiation and taste bud regeneration in the posterior tongue. Age‐related macrophage polarization remodeling, marked by the accumulation of pro‐inflammatory M1 macrophages, contributes to a Thbs1‐enriched inhibitory niche that limits taste cell growth and differentiation ...
Wandong Zhao   +15 more
wiley   +1 more source

Transcriptomic Insights into Tumor Necrosis Factor α's Role in the Fibrosis-Related Processes of Equine Endometrial Fibroblasts. [PDF]

open access: yesInt J Mol Sci
Sadowska A   +5 more
europepmc   +1 more source

Creb3l1 Overexpression Improves Flexor Tendon Repair in Aged Rats

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Aging impairs flexor tendon repair, with aged tendons showing reduced Col1a1 and Sparc expression and compromised mechanical properties. The transcription factor Creb3l1 binds both gene promoters and drives their expression; its overexpression restores Col1a1 and Sparc levels and improves the gliding function, healing strength, and elastic modulus of ...
Qian Qian Yang   +4 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry   +27 more
wiley   +1 more source

From Past Outbreaks to Future Threats: Detecting Medical Conspiracy Theories With LLMs and Limited Labels

open access: yesExpert Systems, Volume 43, Issue 9, September 2026.
ABSTRACT Online dissemination of conspiracy theories (CTs) during epidemics poses significant risks to public health. This paper addresses the problem of detecting CTs in social media posts with an emphasis on the resource‐constrained scenarios characterized by the scarcity of labelled datasets and expert annotations, and the lack of computational ...
Ipek Baris Schlicht   +4 more
wiley   +1 more source

Psychometric properties of the Feedback Orientation Scale in the clinical workplace of health professions students. [PDF]

open access: yesInt J Med Educ
Fuentes-Cimma J   +5 more
europepmc   +1 more source

Intercultural Competence Development Through Tourism: A Study of Czech Visitors to France

open access: yesInternational Journal of Training and Development, Volume 30, Issue 3, Page 270-279, September 2026.
ABSTRACT This study examines international travel as a context for informal intercultural learning and the development of intercultural competence, aligning with the broader goals of training and development. Using the Cross‐Cultural Adaptability Inventory (CCAI), this research assesses changes in four dimensions—Emotional Resilience, Flexibility ...
Renata Cuhlova   +2 more
wiley   +1 more source

Identification of Siderophores With Unexpected Antibacterial Properties From Actinoplanes teichomyceticus

open access: yesChemBioChem, Volume 27, Issue 15, 14 August 2026.
Here, we report isolation of acyl‐desferrioxamines from Actinoplanes teichomyceticus as a mixture of iron and aluminum complexes. The fraction containing these molecules exhibited antibacterial activity. We synthesized these molecules and found that they only exhibited antibacterial activity in the presence of aluminum.
Abiodun S. Oyedele   +7 more
wiley   +1 more source

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