Results 81 to 90 of about 1,295 (151)

Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS

, 1991
Infections caused by cytomegalovirus (CMV) resistant in vitro to ganciclovir, defined as requiring \u3e6 μmol of ganciclovir for ED50 have developed in some AIDS patients with progressive CMV retinitis despite chronic ganciclovir therapy.
P. V. Whitmore, J. J. O'Donnell, Feinberg, Judith, O\u27Donnell, James J., D. Parenti, Jacobson, Mark A., Parenti, David, M. A. Jacobson, Whitmore, Paul V., J. Feinberg, R. D. Miner, W. L. Drew, Drew, W. Lawrence, Miner, Richard D.   +13 more
core   +1 more source

Conformational states of HIV-1 reverse transcriptase for nucleotide incorporation vs. pyrophosphorolysis – binding of foscarnet [PDF]

, 2016
HIV-1 reverse transcriptase (RT) catalytically incorporates individual nucleotides into a viral DNA strand complementing an RNA or DNA template strand; the polymerase active site of RT adopts multiple conformational and structural states while performing
Kalyan Das, Anita R. Maguire, Arnold, Eddy, Anita R. Maguire (1444246), Jan Balzarini, Das, Kalyan, Miller, Matthew T., Jan Balzarini (161754), Jeffrey J. DeStefano (13415), Matthew T. Miller, Kalyan Das (1338543), Eddy Arnold (380419), Maguire, Anita R., Matthew T. Miller (2818933), Balzarini, Jan, Jeffrey J. DeStefano, Eddy Arnold, DeStefano, Jeffrey J.   +17 more
core   +1 more source

Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient

, 2012
We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant ...
Schuurmans, Macé M, Gaspert, Ariana, Tischler, Verena, Boehler, Annette   +3 more
core   +1 more source

Intravitreal foscarnet is an effective adjunct after systemic therapy failure in pediatric antiviral-resistant cytomegalovirus retinitis

Journal of International Medical Research
This report describes the case of a school-aged male child with T-cell acute lymphoblastic leukemia who developed cytomegalovirus retinitis despite systemic antiviral therapy.
Iden Amiri, Pooja Shah, Mohammad Soleimani, Alice Yang Zhang   +3 more
doaj   +1 more source

Foscarnet-induced penile ulcer in a patient with cytomegalovirus coinfection refractory to ganciclovir and Clostridioides difficile: A case report

IDCases
Coinfections by cytomegalovirus and Clostridioides difficile are rare and can be life-threatening, especially in immunosuppressed patients. Their symptoms often overlap, thus generating a great diagnostic challenge, with the need for multiple diagnostic ...
John Jairo Cardeño-Sánchez, Mariana Montoya-Castillo, Juan Ricardo Cadavid-Castrillón, Luis Felipe Higuita-Gutiérrez   +3 more
doaj   +1 more source

Traitement de 2éme ligne par Foscarnet des infections à Cytomégalovirus (CMV) chez les patients Allogreffes [PDF]

, 2015
INTRODUCTIONLes infections a cytomégalovirus sont des complications fréquentes aprés allogreffe de cellules souches hématopoeitiques. Le traitement de premiére intention reste le Ganciclovir, mais ce produit est asocié a des cytopénies ssévéres voir des ...
, A.Toma, S.Maury, C.Cordonier, C.Pautas, Alami Drideb, Noufissa   +1 more
core  

Human Herpesvirus-6 Pneumonitis around the Engraftment of Cord Blood Transplantation following Foscarnet Prophylaxis in a Patient with Acute Leukemia

Case Reports in Hematology, 2015
Human herpesvirus-6 (HHV-6) reactivation is sometimes observed in immunocompromised patients, especially after allogeneic stem cell transplantation. The complications of HHV-6 reactivation in this setting are mainly recognized as HHV-6 encephalitis.
Takashi Ishio, Tomoyuki Endo, Kohei Okada, Akio Shigematsu, Satoshi Hashino, Takanori Teshima   +5 more
doaj   +1 more source

Delayed-onset cytomegalovirus retinitis after 0.2 µg/day fluocinolone acetonide implantation: a case series

Journal of Ophthalmic Inflammation and Infection
Purpose To describe the clinical features and outcomes of cytomegalovirus retinitis (CMVR) presenting after intravitreal fluocinolone acetonide (FAc) implantation.
Anamika Patel, Ilaria Testi, Carlos Pavesio   +2 more
doaj   +1 more source

Concurrent Use of Ganciclovir and Foscarnet to Treat Cytomegalovirus Infection in AIDS Patients

, 1993
Ten patients with AIDS and progressive cytomegalovirus disease were treated with ganciclovir and foscarnet concurrently. The patients had received ganciclovir and foscarnet monotherapy a median of 330 days before receiving combination therapy for a ...
Dieterich, Douglas T, Lew, Edward A, M. A. Poles, Poles, Michael A, Murphy, Robert, R. Murphy, E. A. Lew, K. Naughton, Naughton, Katie, A. Addessi, Friedberg, Dorothy N, D. T. Dieterich, J. T. Holbrook, Mendez, Paul E, D. N. Friedberg, P. E. Mendez, Holbrook, Janet T, Addessi, Adrienne   +17 more
core   +1 more source

Management of CMV encephalitis with persistent CSF CMV DNA in a patient with HIV: a case report of successful treatment with ganciclovir–foscarnet combination therapy

BMC Infectious Diseases
Background Cytomegalovirus (CMV) is a common opportunistic pathogen in immunocompromised individuals and can lead to significant mortality and morbidity via end-organ involvements.
Elif Tanyel, Cengizhan Tanyel, Server Sena Ersarı, Derya Seyman, Hande Berk Cam   +4 more
doaj   +1 more source