Results 81 to 90 of about 420,357 (288)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The Second Banking Directive: Conflicts, Choices, and Long-Term Goals [PDF]

, 1992
Täby kommun har sommaren 2013 infört en för Sverige ny dagvattenreningsteknik i form av en flytande våtmark, som har anlagts i Rönningesjön. Tekniken kan förklaras som en hybrid, där de biologiska reningsprocesserna liknar en naturlig våtmark ...
Matthews, Barbara C.
core   +2 more sources

Statutory and regulatory requirements in the process of mineral mining in Ukraine. Review and analysis [PDF]

, 2019
Purpose. Compliance of statutory and regulatory requirements as for mineral mining, made while subsurface using, mines inspectorating, bringing to responsibility, and creating prerequisites for providing legal guarantees of those who mine the deposits ...
Kirin, R
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Factors Affecting the Rapid Growth of Islamic Banking System: A Comparative Ratio Analysis of Selected Banks of Pakistan

The Islamic Culture, 2020
Banking industry acts as mean of support of contemporary trade and business, stand-in as a link, to endow with a key foundation of monetary intermediation.
Nighat Moin, Muhammad Furqan, Zohra Muhammad Ali   +2 more
doaj  

Aggregating Impact: A Funder's Guide to Mission Investment Intermediaries [PDF]

, 2007
This report provides a guide to mission investment intermediaries, organizations that collect capital from multiple sources and reinvest it in people and enterprises, whether nonprofit or for-profit, that deliver both social impact and financial returns.
Mark R. Kramer, Sarah Cooch
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Analisis Lendutan Model Pelat Fleksibel dengan Tiang Perbesaran Ujung dan Pelat Tidak Rapat Tanah Pada Tanah Pasir

Semesta Teknika, 2015
Problems in sandy soil may occur when sand has low density, uniform gradation and thick deposit. Flexible plate foundation may used in this condition but plate deflection still high.
Edi Hartono
doaj  

Research on Application of Dredging Technology for Steel Pipe Pile Under Complex Sea Conditions in Deep Sea

南方能源建设
[Objective] With the promotion of carbon peak and carbon neutrality strategy, offshore wind power has ushered in a period of rapid growth. In 2023, more than 87 offshore wind power project sites in various provinces and cities across the country have ...
Jianjun CHEN
doaj   +1 more source

Jia Ruskaja: carte private e carte pubbliche. L'archivio dell'Accademia Nazionale di Danza di Roma

Danza e Ricerca, 2017
After the census and the reorganisation of the documents of the Accademia Nazionale di Danza (AND) in Rome it was possible to analyse the archival nature of their papers.
Gianluca Bocchino
doaj   +1 more source