Results 111 to 120 of about 7,389,079 (292)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Navigating uncertainty: Pre‑service foundation phase teachers ’reflections on readiness to teach reading

Perspectives in Education
South Africa faces a major challenge in improving early literacy instruction, as reading proficiency in the foundation phase is essential for later academic success.
Sibhekinkosi Anna Nkomo, Raihaana Chothia   +1 more
doaj   +1 more source

Quantum theory phase space foundations

We give a review of concepts related to connection of classical and quantum theories, from the phase space perspective. Quantum theory is described by non-commutative operators of coordinates and momenta, results in values having a certain probability, hence resembling the classical statistical theory in which coordinates and momenta are well ...
Davidović, Miloš D., Davidović, Ljubica D., Davidović, Milena D.   +2 more
openaire   +2 more sources

Sotho for Foundation Phase 3A

, 2015
Exam paper for B.Ed.(Foundation Phase ...
University of Johannesburg
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Sotho for foundation phase 2A

, 2015
Exam paper for first semester B.Ed.(Foundation ...
Mathibela,L.,Mr., Mokgathi,R.,Ms.
core   +2 more sources

Refining preservice teachers’ vocabulary instruction through coaching and reflection using mixed reality simulations

Reading & Writing
Background: Effective vocabulary instruction underpins learners’ oral and reading comprehension; however, persistent comprehension difficulties in South African schools linked to limited vocabulary teaching highlight the need to strengthen preservice ...
Nthabiseng T. Tsotetsi
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Exploring Satisfaction and Perceived Learning in Physical Therapy Students during Online Learning: A Cross-Sectional Survey

Journal Riphah College of Rehabilitation Sciences
Background: The coronavirus outbreak which occurred in 2019 brought an unprecedented transformation in the education sector, accelerating the shift from traditional face-to-face learning to online platforms.
Ayesha Arshad, Amna Tauqeer, Amina Tariq, Nida Mushtaq, Marwa Asim, Amina Fayyaz   +5 more
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source