Results 31 to 40 of about 106,656 (261)
Frontiers in Aging Neuroscience, 2022 Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive loss of cognitive function, with β-amyloid plaques and neurofibrillary tangles being its major pathological findings.
Maribel Orozco-Barajas +5 more
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Genetic diversity and demographic history of introduced sika deer on the Delmarva Peninsula
Ecology and Evolution, 2019 The introduction of non‐native species can have long‐term effects on native plant and animal communities. Introduced populations are occasionally not well understood and offer opportunities to evaluate changes in genetic structure through time and major ...
David M. Kalb +3 more
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Frontiers in Genetics, 2019 Non-syndromic hearing loss (NSHL) is a hereditary disorder that affects many populations. Many genes are involved in NSHL and the mutational load of these genes often differs among ethnic groups. Claudin-14 (CLDN14), a tight junction protein, is known to
Walaa Kamal Eldin Mohamed +7 more
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Frontiers in Microbiology, 2022 Pozas Rojas is a hydrological system comprising nine isolated shallow ponds and a deep lagoon, which were temporally merged in 2010 by increased rainfall due to a tropical cyclone.
Manuel García-Ulloa +15 more
doaj +1 more source
The founder effect and deleterious genes [PDF]
American Journal of Physical Anthropology, 1969 AbstractDuring the rapid growth of a population from a few founders, a single deleterious gene in a founder can attain an appreciable frequency in later generations. A computer simulation, which has the population double itself in early generations, indicates a lethal could attain a frequency of 0.1.
openaire +3 more sources
Allele frequencies of AVPR1A and MAOA in the Afrikaner population
South African Journal of Science, 2015 The Afrikaner population was founded mainly by European immigrants that arrived in South Africa from 1652. However, female slaves from Asia and Africa and local KhoeSan women may have contributed as much as 7% to this population’s genes.
J. Christoff Erasmus +2 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: Antithrombin (AT) is one of the most important regulator of hemostasis. AT Budapest 3 (ATBp3) is a prevalent type II heparin-binding site (IIHBS) deficiency due to founder effect.
Zsuzsanna Bereczky +9 more
doaj +1 more source
Jurnal Manajemen Teori dan Terapan, 2016 This study objective is to understand the effect involvement of founder family to financial performance (ROA) and firm market value (Tobins Q) in family firm which is listed in BEI (Bursa Efek Indonesia).
Dewi Ariani, Noorlaily Fitdiarini
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Population medical genetics: translating science to the community
Genetics and Molecular Biology, 2019 Rare genetic disorders are currently in the spotlight due to the elevated number of different conditions and significant total number of affected patients.
Roberto Giugliani +21 more
doaj +1 more source