Results 31 to 40 of about 528,283 (301)

Inertia and Change in the Early Years: Employment Relations in Young, High Technology Firms [PDF]

open access: yes, 1996
[Excerpt] This paper considers processes of organizational imprinting in a sample of 100 young, high technology companies. It examines the effects of a pair of initial conditions: the founders\u27 models of the employment relation and their business ...
Baron, James N   +2 more
core   +3 more sources

Genetic variation in three paddlefish (Polyodon spathula Walbaum) stocks based on microsatellite DNA analysis

open access: yesCzech Journal of Animal Science, 2012
There are two stocks of American paddlefish Polyodon spathula in Poland, one in Pogorze and the other in Wasosze. These stocks were established from small quantities of eggs imported from the USA in 1995.
D. Kaczmarczyk, M. Luczynski, P. Brzuzan
doaj   +1 more source

Model worms: knowledge gains and risks associated with the use of model species in parasitological research

open access: yesParasitology, 2023
Model parasite species, whose entire life cycle can be completed in the laboratory and maintained for multiple generations, have played a fundamental role in our understanding of host–parasite interactions. Yet, keeping parasites in laboratory conditions
Robert Poulin
doaj   +1 more source

Correction for founder effects in host-viral association studies via principal components [PDF]

open access: yes, 2012
Viruses such as HIV and Hepatitis C (HCV) replicate rapidly and with high transcription error rates, which may facilitate their escape from immune detection through the encoding of mutations at key positions within human leukocyte antigen (HLA)-specific ...
James, I.R.   +2 more
core   +2 more sources

Recurrent genetic variants and prioritization of variants of uncertain clinical significance associated with hereditary breast and ovarian cancer in families from the Region of Murcia

open access: yesAdvances in Laboratory Medicine, 2023
Hereditary breast and ovarian cancer (HBOC) follows an autosomal dominant inheritance pattern of cancer susceptibility genes. The risk of developing this disease is primarily associated with germline mutations in the BRCA1 and BRCA2 genes.
Rosado-Jiménez Laura   +12 more
doaj   +1 more source

Genetic diversity and demographic history of introduced sika deer on the Delmarva Peninsula

open access: yesEcology and Evolution, 2019
The introduction of non‐native species can have long‐term effects on native plant and animal communities. Introduced populations are occasionally not well understood and offer opportunities to evaluate changes in genetic structure through time and major ...
David M. Kalb   +3 more
doaj   +1 more source

A Novel Nonsense Mutation (c.414G>A; p.Trp138*) in CLDN14 Causes Hearing Loss in Yemeni Families: A Case Report

open access: yesFrontiers in Genetics, 2019
Non-syndromic hearing loss (NSHL) is a hereditary disorder that affects many populations. Many genes are involved in NSHL and the mutational load of these genes often differs among ethnic groups. Claudin-14 (CLDN14), a tight junction protein, is known to
Walaa Kamal Eldin Mohamed   +7 more
doaj   +1 more source

Has HIV evolved to induce immune pathogenesis? [PDF]

open access: yes, 2008
Human immunodeficiency virus (HIV) induces a chronic generalized activation of the immune system, which plays an important role in the pathogenesis of AIDS.
Bartha, István   +2 more
core   +1 more source

Allele frequencies of AVPR1A and MAOA in the Afrikaner population

open access: yesSouth African Journal of Science, 2015
The Afrikaner population was founded mainly by European immigrants that arrived in South Africa from 1652. However, female slaves from Asia and Africa and local KhoeSan women may have contributed as much as 7% to this population’s genes.
J. Christoff Erasmus   +2 more
doaj   +1 more source

Sodium Channel Myotonia Due to Novel Mutations in Domain I of Nav1.4

open access: yesFrontiers in Neurology, 2020
Sodium channel myotonia is a form of muscle channelopathy due to mutations that affect the Nav1.4 channel. We describe seven families with a series of symptoms ranging from asymptomatic to clearly myotonic signs that have in common two novel mutations, p.
Serena Pagliarani   +14 more
doaj   +1 more source

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