Results 41 to 50 of about 528,283 (301)
Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion [PDF]
, 1998 Linkage disequilibrium has been a powerful tool in identifying rare disease alleles in human populations. To date, most research has been directed to isolated populations which have undergone a bottleneck followed by rapid exponential expansion.
Laan, Maris +3 more
core +1 more source
Genetic depletion does not prevent rapid evolution in island‐introduced lizards
Ecology and Evolution, 2023 Experimental introductions of species have provided some of the most tractable examples of rapid phenotypic changes, which may reflect plasticity, the impact of stochastic processes, or the action of natural selection.
Stéphanie Sherpa +6 more
doaj +1 more source
The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]
, 2006 BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E. +2 more
core +2 more sources
Jurnal Manajemen Teori dan Terapan, 2016 This study objective is to understand the effect involvement of founder family to financial performance (ROA) and firm market value (Tobins Q) in family firm which is listed in BEI (Bursa Efek Indonesia).
Dewi Ariani, Noorlaily Fitdiarini
doaj +1 more source
The founder effect and deleterious genes [PDF]
American Journal of Physical Anthropology, 1969 AbstractDuring the rapid growth of a population from a few founders, a single deleterious gene in a founder can attain an appreciable frequency in later generations. A computer simulation, which has the population double itself in early generations, indicates a lethal could attain a frequency of 0.1.
openaire +3 more sources
Organizational Mortality of Small Firms: The Effects of Entrepreneurial Age and Human Capital [PDF]
, 1990 This paper addresses the issue of internal determination of organizational outcomes. It is argued that in small and simply structured organizations a considerable proportion of the variance in organizational activities and outcomes is associated with ...
Aldrich, Howard +25 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
UNDERSTANDING THE RELATIONSHIP BETWEEN FOUNDER-CEOS AND FIRM PERFORMANCE [PDF]
, 2008 While previous empirical literature has examined the effect of founder-CEOs on firm performance, it has largely ignored the effect of firm performance on founder-CEO status.
Adams, Renée B. +2 more
core
Modeling the ecology and evolution of biodiversity: Biogeographical cradles, museums, and graves [PDF]
, 2018 Individual processes shaping geographical patterns of biodiversity are increasingly understood, but their complex interactions on broad spatial and temporal scales remain beyond the reach of analytical models and traditional experiments.
Cassemiro, Fernanda A. S. +9 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie +4 more
wiley +1 more source